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. 1988 Aug;79(4):382-4.
doi: 10.1007/BF00282183.

Linkage relationship between retinoschisis and four marker loci

G Gellert  1 , J Peterson, M Krawczak, B Zoll
Affiliations

Linkage relationship between retinoschisis and four marker loci

G Gellert et al. Hum Genet. 1988 Aug.

Abstract

The linkage relationship between the locus for juvenile retinoschisis (RS) and four X-chromosomal marker loci DXS9 (RC8), DXS16 (XUT23), DXS41 (99-6), and DXS43 (D2) has been studied in six families showing a history of this disease. Recombination with RS was found for all marker loci except DXS9. The maximum lod score is zeta = 2.66 for RS vs. DXS9 at a recombination fraction of theta = 0.0. Multipoint linkage analysis was performed and the locus order best supported by our data is: RS - DXS9 - DXS43 - DXS16 - DXS41.

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References

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