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. 2017 Oct 9;27(19):R1047-R1049.
doi: 10.1016/j.cub.2017.08.001.

Transvection

Takashi Fukaya  1 , Michael Levine  2
Affiliations

Transvection

Takashi Fukaya et al. Curr Biol. .

Abstract

Fukaya and Levine explain the basic features of the genetic phenomenon of transvection, a special class of genetic complementation of mutant alleles on homologous chromosomes.

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Figures

Figure 1
Figure 1. Transvection in Drosophila
(A) Transvection in bx34e/Ubx1 trans-heterozygotes. Intronic abx and BRE enhancers on the Ubx1al-lele activate transcription from the bx34e allele in trans. (B) Loss of cis-linked promoter augments transvection. UbxMx6 mutation consists of a 3.4 kb deletion including the Ubx promoter. (C) 5′ wing and body enhancers on the promoter-less allele activate transcription from the enhancer-less allele in trans. W, wing enhancer; B, body enhancer; Br, bristle enhancer; T, tarsal claw enhancer. (D) Insulator DNAs facilitate transvection at yellow.
See this image and copyright information in PMC

References

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