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. 2017 Oct 10;17(1):131.
doi: 10.1186/s12890-017-0471-x.

Chronic obstructive pulmonary disease, bronchial asthma and allergic rhinitis in the adult population within the commonwealth of independent states: rationale and design of the CORE study

Yuriy Feshchenko  1 , Liudmyla Iashyna  1 , Damilya Nugmanova  2 , Olga Gyrina  3 , Maryna Polianska  1 , Alexander Markov  4 , Maryna Moibenko  4 , Janina Makarova  5 , Luqman Tariq  6 , Marcelo Horacio S Pereira  7 , Eljan Mammadbayov  8 , Irada Akhundova  8 , Averyan Vasylyev  4
Affiliations

Chronic obstructive pulmonary disease, bronchial asthma and allergic rhinitis in the adult population within the commonwealth of independent states: rationale and design of the CORE study

Yuriy Feshchenko et al. BMC Pulm Med. .

Erratum in

Abstract

Background: Main treatable Chronic Respiratory Diseases (CRDs) like Chronic Obstructive Pulmonary Disease (COPD), Bronchial Asthma (BA) and Allergic Rhinitis (AR) are underdiagnosed and undertreated worldwide. CORE study was aimed to assess the point prevalence of COPD, BA and AR in the adult population of major cities of Commonwealth of Independent States (CIS) countries - Azerbaijan, Kazakhstan, and Ukraine based on study questionnaires and/or spirometry, and to document risk factors, characterize the COPD, BA and AR population to provide a clearer "epidemiological data".

Methods: A descriptive, cross-sectional, population-based epidemiological study conducted from 2013 to 2015 with two-stage cluster geographical randomization. Interviewers conducted face-to-face visits at respondent's household after informed consent and eligibility assessment including interviews, anthropometry, spirometry (with bronchodilator test) and completion of disease-specific questionnaires.

Results: Two thousand eight hundred forty-two respondents (Ukraine: 964 from Ukraine; 945 from Kazakhstan; 933 Azerbaijan) were enrolled. Mean age was 40-42 years and males were 37%-42% across three countries. In Kazakhstan 62.8% were Asians, but in Ukraine and in Azerbaijan 99.7% and 100.0%, respectively, were Caucasians. Manual labourers constituted 40.5% in Ukraine, 22.8% in Kazakhstan and 22.0% in Azerbaijan, while office workers were 16.1%, 31.6% and 36.8% respectively. 51.3% respondents in Ukraine, 64.9% in Kazakhstan and 69.7% in Azerbaijan were married.

Conclusion: CORE study collected information that can be supportive for health policy decision makers in allocating healthcare resources in order to improve diagnosis and management of CRDs. The detailed findings will be described in future publications.

Trial registration: Study Protocol Summary is disclosed at GlaxoSmithKline Clinical Study Register on Jun 06, 2013, study ID 116757 .

Keywords: Allergic rhinitis; Azerbaijan; Bronchial asthma; COPD; Chronic respiratory diseases; Kazakhstan; Prevalence; Risk factors; Study design; Ukraine.

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Conflict of interest statement

Ethics approval and consent to participate

The study was reviewed and approved by Independent Ethic Committee in Kazakhstan (Central Commission for Ethics at the Ministry of Health of the Republic of Kazakhstan) and by Local Ethic Committees in Kazakhstan, Azerbaijan and Ukraine (Ethic Committee at Semey State Medical University, Almaty, Kazakhstan; Ethic Committee at Scientific Research Institute of Lung Diseases in Baku, Azerbaijan; Commission for Ethics at National Institute of Phthisiology and Pulmonology F.G. Yanovsky of NAMS, Kiev, Ukraine; Commission for Ethics at Center for Primary Health Care #2 of Shevchenko District, Kiev, Ukraine), according to the local legal requirements. Written informed consent was obtained from each participant before any procedures or data collection related to the study.

Consent for publication

Not applicable.

Competing interests

The study was sponsored by GlaxoSmithKline (GSK) marketing a number of treatments for COPD, Allergic Rhinitis, and Asthma. DN, YF, MP, LY, OG, EM, IA report grants from GSK, during the conduct of the study and personal fees from GlaxoSmithKline outside the submitted work. MM, JM are employees of GSK. AV and LT are GSK employees and shareholder. AM and MHSP were employees of GSK at the time this research was conducted.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
Details of the recruitment phase. The number of enrolled participants is presented overall and by country
Fig. 2
Fig. 2
Stratified random cluster sampling procedure. SEC (Study Executive Committee) randomly selected districts in each city. Each city district was divided into squares (on the city map). Similar random strategy was applied for map squares within districts and then for streets within map squares and then for households within streets
See this image and copyright information in PMC

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