Unilateral Ocular Manifestations of Vogt-Koyanagi-Harada Disease

Abstract

Purpose: To describe a case of unilateral Vogt-Koyanagi-Harada (VKH) disease and associated multimodal imaging.

Methods: Retrospective case report.

Results: A 50-year-old Hispanic male presented with three days of painless decreased vision in his left eye, headache, and decreased hearing. His visual acuity was 20/20 in the right eye and counting fingers in the left eye. Examination of his right eye was unremarkable. Funduscopic examination of his left eye revealed multiple serous retinal detachments. Fluorescein angiography demonstrated late multifocal pinpoint hyperfluorescence in his left eye and a diagnosis of VKH disease was made. He was treated with oral prednisone. Serial re-examination demonstrated resolution of the serous retinal detachments and a taper of his oral prednisone was initiated with improvement of his visual acuity to 20/25.

Conclusions: Our patient had imaging and a clinical course that was consistent with VKH disease. This unilateral presentation may represent a clinical variant of VKH disease.

Keywords: Vogt–Koyanagi–Harada disease; immunosuppression; multimodal imaging; non-infectious uveitis, uveitis.