New pyridocarbazole alkaloids from Strychnos nitida
- PMID: 29022360
- DOI: 10.1080/14786419.2017.1385016
New pyridocarbazole alkaloids from Strychnos nitida
Abstract
Phytochemical investigation of Strychnos nitida has led to the isolation of three new racemic pyridocarbazole alkaloids, (±)-stritidas A-C (1-3) and three known monoterpenoid indole alkaloids (4-6). Compounds 2 and 3 represent the first examples of pyridocarbazole alkaloids featuring an N-2-hydroxyethyl moiety. Their structures were determined by combined spectroscopic data (MS, UV, IR and NMR) and chemical methods.
Keywords: Strychnos nitida; monoterpenoid indole alkaloids; pridocarbazole alkaloids.
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