Hysteroscopic Management of Asherman's Syndrome

Abstract

In developed countries Asherman's syndrome is almost always the result of a prior intrauterine operative trauma. This is often asymptomatic but may result in hypo- or amenorrhea and can contribute to infertility and pregnancy complications. We review their etiology, clinical implications, and systems proposed to classify their extent. The numerous methods reported for performing lysis of intrauterine adhesions are summarized along with clinical results. Current strategies to prevent recurrence of intrauterine adhesions have not been conclusively shown to be clinically effective, but the potential for endometrial regeneration using stem cells is an exciting modality under investigation.

Keywords: Adhesion reformation; Asherman's syndrome; Hysteroscopy; Infertility; Intrauterine adhesions; Lysis of adhesions; Menstrual abnormalities; Pregnancy complications.