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Comment
. 2017 Dec 1;46(6):2097-2099.
doi: 10.1093/ije/dyx192.

Misconceptions on the use of MR-Egger regression and the evaluation of the InSIDE assumption

Jack Bowden  1
Affiliations
Comment

Misconceptions on the use of MR-Egger regression and the evaluation of the InSIDE assumption

Jack Bowden. Int J Epidemiol. .
No abstract available

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References

    1. Slob EAW, Groenen PJF, Thurik AR, Rietveld CA. A note on the use of Egger regression in Mendelian randomization studies. Int J Epidemiol 2017;46:2094–97. - PubMed
    1. Bowden J, Davey Smith G, Burgess S. Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression. Int J Epidemiol 2015;44:512–25. - PMC - PubMed
    1. Bowden J, Burgess S, Davey Smith G. Response to Hartwig and Davies. Int J Epidemiol 2016;45:1679–80. - PMC - PubMed
    1. Hartwig FP, Davies NM. Why internal weights should be avoided (not only) in MR-Egger regression. Int J Epidemiol 2016;45:1676–78. - PubMed
    1. Bowden J, Del Greco M, Minelli C, Davey Smith G, Sheehan N, Thompson J. A framework for the investigation of pleiotropy in two‐sample summary data Mendelian randomization. Stat Med 2017;36:1783–802. - PMC - PubMed

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