A note on the use of Egger regression in Mendelian randomization studies

Eric A W Slob^{1

2}, Patrick J F Groenen^{1

3}, A Roy Thurik^{1

2

4}, Cornelius A Rietveld^{1

2}

Affiliations

¹ Erasmus University Rotterdam Institute for Behavior and Biology.
² Department of Applied Economics.
³ Econometric Institute, Erasmus School of Economics, Rotterdam, The Netherlands.
⁴ Montpellier Business School, Montpellier, France.

Comment

Eric A W Slob et al. Int J Epidemiol. 2017.

. 2017 Dec 1;46(6):2094-2097.

doi: 10.1093/ije/dyx191.

Eric A W Slob^{1

2}, Patrick J F Groenen^{1

3}, A Roy Thurik^{1

2

4}, Cornelius A Rietveld^{1

2}

¹ Erasmus University Rotterdam Institute for Behavior and Biology.
² Department of Applied Economics.
³ Econometric Institute, Erasmus School of Economics, Rotterdam, The Netherlands.
⁴ Montpellier Business School, Montpellier, France.

No abstract available

Comment in

Misconceptions on the use of MR-Egger regression and the evaluation of the InSIDE assumption.
Bowden J. Bowden J. Int J Epidemiol. 2017 Dec 1;46(6):2097-2099. doi: 10.1093/ije/dyx192. Int J Epidemiol. 2017. PMID: 29025021 Free PMC article. No abstract available.

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression.
Bowden J, Davey Smith G, Burgess S. Bowden J, et al. Int J Epidemiol. 2015 Apr;44(2):512-25. doi: 10.1093/ije/dyv080. Epub 2015 Jun 6. Int J Epidemiol. 2015. PMID: 26050253 Free PMC article.
A framework for the investigation of pleiotropy in two-sample summary data Mendelian randomization.
Bowden J, Del Greco M F, Minelli C, Davey Smith G, Sheehan N, Thompson J. Bowden J, et al. Stat Med. 2017 May 20;36(11):1783-1802. doi: 10.1002/sim.7221. Epub 2017 Jan 23. Stat Med. 2017. PMID: 28114746 Free PMC article.