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Review
. 2017 Aug 31:6:1616.
doi: 10.12688/f1000research.11701.1. eCollection 2017.

Recent advances in in vitro fertilization

Robert Casper  1   2   3 , Jigal Haas  1 , Tzu-Bou Hsieh  1 , Rawad Bassil  1 , Chaula Mehta  1
Affiliations
Review

Recent advances in in vitro fertilization

Robert Casper et al. F1000Res. .

Abstract

The field of assisted reproductive technology is rapidly progressing with many new advances in the last decade. The present review discusses methods to improve oocyte quality in older women and new stimulation protocols that may improve the number of mature oocytes retrieved during an in vitro fertilization cycle. We will discuss the present use of pre-implantation genetic screening (PGS) and finally focus on some new methods to determine endometrial receptivity. The focus of this review is to point out areas of technology that may be controversial or are new enough to require proper controlled studies for validation.

Keywords: Co-enzyme Q10; IVF; Letrozole; PGS.

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Conflict of interest statement

Competing interests: RFC declares that he is on the scientific advisory board of OvaScience and has stock options.No competing interests were disclosed.No competing interests were disclosed.

References

    1. Ben-Meir A, Burstein E, Borrego-Alvarez A, et al. : Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging. Aging Cell. 2015;14(5):887–95. 10.1111/acel.12368 - DOI - PMC - PubMed
    1. O’Connor KA, Holman DJ, Wood JW: Declining fecundity and ovarian ageing in natural fertility populations. Maturitas. 1998;30(2):127–36. 10.1016/S0378-5122(98)00068-1 - DOI - PubMed
    1. Titus S, Li F, Stobezki R, et al. : Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans. Sci Transl Med. 2013;5(172):172ra21. 10.1126/scitranslmed.3004925 - DOI - PMC - PubMed

    2. F1000 Recommendation

    1. Dumollard R, Ward Z, Carroll J, et al. : Regulation of redox metabolism in the mouse oocyte and embryo. Development. 2007;134(3):455–65. 10.1242/dev.02744 - DOI - PubMed
    1. Crane FL: Biochemical functions of coenzyme Q 10. J Am Coll Nutr. 2001;20(6):591–8. 10.1080/07315724.2001.10719063 - DOI - PubMed

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