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Case Reports
. 2017 Sep 8;5(10):1706-1711.
doi: 10.1002/ccr3.1131. eCollection 2017 Oct.

Split high-dose oral levothyroxine treatment as a successful therapy option in myxedema coma

Suranut Charoensri  1   2 , Chutintorn Sriphrapradang  1 , Hataikarn Nimitphong  1
Affiliations
Case Reports

Split high-dose oral levothyroxine treatment as a successful therapy option in myxedema coma

Suranut Charoensri et al. Clin Case Rep. .

Abstract

High-dose intravenous thyroxine (T4) is the preferable treatment for myxedema coma. We describe the clinical course of a 69-year-old man who presented with myxedema coma and received oral levothyroxine (LT4) therapy (1 mg) in a split dose. This suggests split high-dose oral LT4 as a therapeutic option in myxedema coma.

Keywords: Coma; hypothyroidism; myxedema; oral administration; thyroxine.

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Figures

Figure 1
Figure 1
Clinical response after initiation of split high‐dose oral LT4 (at day 28 of admission) with 0.2 mg LT4 orally every 8 h for five consecutive doses, then maintenance with 0.1 mg/day. °C, degree celsius; BT, body temperature; bpm, beats per minute; FT4, free thyroxine; HR, heart rate.
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