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. 1988 Nov 7;239(2):185-9.
doi: 10.1016/0014-5793(88)80913-x.

Expression of K channels in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting beta-cell line, HIT T15

F M Ashcroft  1 , S J Ashcroft, P O Berggren, C Betzholz, P Rorsman, G Trube, M Welsh
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Free article

Expression of K channels in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting beta-cell line, HIT T15

F M Ashcroft et al. FEBS Lett. .
Free article

Abstract

Two types of exogenous K channel were identified in Xenopus laevis oocytes injected with poly(A+) mRNA from the insulin-secreting cell line HIT T15. One of these was the ATP-regulated K channel (G channel) as evidenced by its conductance and inhibition by tolbutamide. The other resembled the Ca-activated K channel from beta-cells.

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