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. 2018 Feb:193:14-20.e31.
doi: 10.1016/j.jpeds.2017.08.077. Epub 2017 Oct 12.

Children as Biomarker Orphans: Progress in the Field of Pediatric Biomarkers

Darla R Shores  1 , Allen D Everett  2
Affiliations

Children as Biomarker Orphans: Progress in the Field of Pediatric Biomarkers

Darla R Shores et al. J Pediatr. 2018 Feb.
No abstract available

Keywords: biofluids; biorepository; biospecimens; surrogate markers.

PubMed Disclaimer

Conflict of interest statement

The other authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
The proportion of publications by body system from 2012–2016
Figure 2
Figure 2
The number of pediatric biomarker publications by body fluid or tissue type from 2012–2016. Multiple tissue types were used in some manuscripts, which are represented more than once in the graph.
See this image and copyright information in PMC

References

    1. Yajnik C. Interactions of perturbations in intrauterine growth and growth during childhood on the risk of adult-onset disease. The Proceedings of the Nutrition Society. 2000;59:257–65. - PubMed
    1. Shonkoff JP, Boyce WT, McEwen BS. Neuroscience, molecular biology, and the childhood roots of health disparities: building a new framework for health promotion and disease prevention. Jama. 2009;301:2252–9. - PubMed
    1. Savage WJ, Everett AD. Biomarkers in pediatrics: children as biomarker orphans. Proteomics Clinical applications. 2010;4:915–21. - PubMed
    1. Bortolotti F, Muratori L, Jara P, Hierro L, Verucchi G, Giacchino R, et al. Hepatitis C virus infection associated with liver-kidney microsomal antibody type 1 (LKM1) autoantibodies in children. J Pediatr. 2003;142:185–90. - PubMed
    1. Roberts EA. Autoimmune hepatitis from the paediatric perspective. Liver Int. 2011;31:1424–31. - PubMed

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