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Case Reports
. 2018 Jan 1;57(1):53-57.
doi: 10.2169/internalmedicine.9216-17. Epub 2017 Oct 16.

Efficacy of Oxycodone for Dyspnea in End-stage Heart Failure with Renal Insufficiency

Masayuki Tanaka  1 , Hirofumi Maeba  2 , Takeshi Senoo  2 , Junji Iwasaka  2 , Aki Ohkita  3 , Haruna Kita  1 , Kazuki Uchitani  1 , Yasuhiko Hirota  1
Affiliations
Case Reports

Efficacy of Oxycodone for Dyspnea in End-stage Heart Failure with Renal Insufficiency

Masayuki Tanaka et al. Intern Med. .

Abstract

A 67-year-old man with dilated cardiomyopathy and renal insufficiency was admitted to our hospital with dyspnea secondary to end-stage heart failure. We introduced oxycodone for medically refractory dyspnea instead of morphine because of the patient's renal insufficiency. After the administration of oxycodone, his dyspnea was alleviated without any adverse opioid effects, such as respiratory depression. After treating his heart failure, he was able to leave the intensive care unit. Oxycodone may therefore be a reliable agent for the treatment of dyspnea in patients with end-stage heart failure and renal insufficiency.

Keywords: dyspnea; oxycodone; terminal-stage heart failure.

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Figures

Figure 1.
Figure 1.
A chest X-ray reveals cardiomegaly with mild pulmonary congestion and no pleural effusion.
Figure 2.
Figure 2.
A 12-lead electrocardiogram shows all pacing rhythm without any newly developed ST-T changes in comparison to the findings of the patient’s previously recorded electrocardiogram.
Figure 3.
Figure 3.
Transthoracic echocardiography demonstrates a severely dilated left ventricle.
Figure 4.
Figure 4.
Clinical course including medications, changes in the respiratory rate and the modified Borg Scale score, and various laboratory markers while in our coronary care unit.
See this image and copyright information in PMC

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