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Case Reports
. 2017 Sep 26;11(3):559-563.
doi: 10.1159/000479312. eCollection 2017 Sep-Dec.

A Case of Basaloid Squamous Cell Carcinoma of Polypoid Type in the Esophagus

Affiliations
Case Reports

A Case of Basaloid Squamous Cell Carcinoma of Polypoid Type in the Esophagus

Ki Hun Lee et al. Case Rep Gastroenterol. .

Abstract

Basaloid squamous cell carcinoma of the esophagus is very rare. Further, polypoid type of esophageal cancer is also rare. We have recently treated a case of basaloid squamous cell carcinoma which presented as a 1.3-cm esophageal polyp. A 48-year-old woman was referred to our hospital because of a polypoid mass at 36 cm distance from the upper incisor on endoscopic examination, and the result of the biopsy was basaloid squamous cell carcinoma. The patient underwent Ivor Lewis operation with lymph node dissection. Two basaloid squamous cell carcinomas, of 1.3 and 0.4 cm, were diagnosed in the final pathologic examination. Regular periodic follow-up showed no evidence of recurrence or metastasis in the 5-month postoperative period.

Keywords: Esophagus; Polyps; Squamous cell carcinoma; Surgery.

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Figures

Fig. 1
Fig. 1
The endoscopy shows a 1.3-cm Lugol-voided polyp and multiple Lugol-voided flat lesions in the lower esophagus.
Fig. 2
Fig. 2
The macroscopic view of the surgically resected specimen. a The macroscopic view of the surgically resected specimen shows a 1.3 × 1 cm polyp at 2 cm distance from the gastroesophageal junction. b Mapping of the surgically resected specimen reveals a 1.3 × 1 cm and a 0.4-cm basaloid squamous cell carcinoma (black color). Multiple separated dysplastic areas were noted (green color).
Fig. 3
Fig. 3
Microscopic examination of the resected specimen. a The tumor consists of basaloid cells showing oval to round nuclei with open pale chromatin features. Frequent mitotic figures are also noted (HE stain, ×200). b The tumor shows a solid growth pattern with a comedo-like necrosis structure (left lower portion) (HE stain, ×10).

References

    1. Cardesa A, Zidar N, Ereño C. Basaloid squamous cell carcinoma. In: Barnes L, Eveson JW, Reichart P, Sidrasky D, Kleihues P, Sobin LH, editors. Pathology and Genetics of Head and Neck Tumours. World Health Organization Classification of Tumours. Lyon: IARC Press; 2005. pp. 124–125.
    1. Wain SL, Kier R, Wollmer RT, et al. Basaloid-squamous carcinoma of the tongue, hypopharynx, and larynx: report of 10 cases. Hum Pathol. 1986;17:1158–1166. - PubMed
    1. Noguchi H, Naomoto Y, Haisa M, Yamatsuji T, Shigemitsu K, Shirakawa Y, et al. Two cases of superficial basaloid squamous carcinoma of the esophagus. Dis Esophagus. 2003;16:342–345. - PubMed
    1. Mori M, Mimori K, Sadanaga N, et al. Polypoid carcinoma of the esophagus. Jpn J Cancer Res. 1994;85:1131–1136. - PMC - PubMed
    1. Olmsted WW, Lichstein JE, Hyams V. Polypoid epithelial malignancies of the esophagus. AJR Am J Roentgenol. 1983;140:921–925. - PubMed

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