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. 2017 Jan 13;7(4):433-440.
doi: 10.1016/j.jtcme.2016.12.014. eCollection 2017 Oct.

Pharmacological properties of Salvia officinalis and its components

Ahmad Ghorbani  1 , Mahdi Esmaeilizadeh  2   3
Affiliations

Pharmacological properties of Salvia officinalis and its components

Ahmad Ghorbani et al. J Tradit Complement Med. .

Abstract

Salvia officinalis (Sage) is a plant in the family of Labiatae/Lamiaceae. It is native to Middle East and Mediterranean areas, but today has been naturalized throughout the world. In folk medicine, S. officinalis has been used for the treatment of different kinds of disorders including seizure, ulcers, gout, rheumatism, inflammation, dizziness, tremor, paralysis, diarrhea, and hyperglycemia. In recent years, this plant has been a subject of intensive studies to document its traditional use and to find new biological effects. These studies have revealed a wide range of pharmacological activities for S. officinalis. Present review highlights the up-to-date information on the pharmacological findings that have been frequently reported for S. officinalis. These findings include anticancer, anti-inflammatory, antinociceptive, antioxidant, antimicrobial, antimutagenic, antidementia, hypoglycemic, and hypolipidemic effects. Also, chemical constituents responsible for pharmacological effects of S. officinalis and the clinical studies on this plant are presented and discussed.

Keywords: Anticancer; Antimutagenic; Flavonoids; Sage; Salvia officinalis.

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Figures

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Graphical abstract
Fig. 1
Fig. 1
Arial parts of Salvia officinalis L.
Fig. 2
Fig. 2
Structure of main flavonoids isolated from Salvia officinalis.
Fig. 3
Fig. 3
Structure of main terpenes and terpenoids isolated from Salvia officinalis.
See this image and copyright information in PMC

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