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. 2017 Sep 18:15:163-169.
doi: 10.1016/j.dib.2017.09.019. eCollection 2017 Dec.

Data on chow, liver tissue and mitochondrial fatty acid compositions as well as mitochondrial proteome changes after feeding mice a western diet for 6-24 weeks

Claudia Einer  1 , Simon Hohenester  2 , Ralf Wimmer  2 , Lena Wottke  2 , Renate Artmann  2 , Sabine Schulz  1 , Christian Gosmann  1 , Alisha Simmons  1 , Christin Leitzinger  1 , Carola Eberhagen  1 , Sabine Borchard  1 , Sabine Schmitt  3 , Stefanie M Hauck  4 , Christine von Toerne  4 , Martin Jastroch  5 , Ellen Walheim  5 , Christian Rust  6 , Alexander L Gerbes  2 , Bastian Popper  7 , Doris Mayr  8 , Max Schnurr  9 , Angelika M Vollmar  10 , Gerald Denk  2 , Hans Zischka  1   3
Affiliations

Data on chow, liver tissue and mitochondrial fatty acid compositions as well as mitochondrial proteome changes after feeding mice a western diet for 6-24 weeks

Claudia Einer et al. Data Brief. .

Abstract

The data presented in this article describe the fatty acid composition of chow, liver tissue and isolated liver mitochondria from mice fed for 6-24 weeks with a high caloric western diet (WD) in comparison to control diet (normal diet, ND). The fatty acid composition was measured via gas chromatography flame ionization detection (GC-FID). Moreover, WD-induced mitochondrial protein changes are presented in this work and were analyzed by mass spectrometry (LC-MS/MS). For further interpretation and discussion of the presented data please refer to the research article entitled "Mitochondrial adaptation in steatotic mice" (Einer et al., 2017) [1].

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References

    1. Einer C. Mitochondrial adaptation in steatotic mice. Mitochondrion. 2017 (in press, https://doi.org/10.1016/j.mito.2017.08.015)) - DOI - PubMed
    1. Tetri L.H. Severe NAFLD with hepatic necroinflammatory changes in mice fed trans fats and a high-fructose corn syrup equivalent. Am. J Physiol. Gastrointest. Liver Physiol. 2008;295(5):G987–G995. - PMC - PubMed
    1. Schulz S. A protocol for the parallel isolation of intact mitochondria from rat liver, kidney, heart, and brain. Methods Mol. Biol. 2015;1295:75–86. - PubMed
    1. Schmitt S. Why to compare absolute numbers of mitochondria. Mitochondrion. 2014;19(Pt. A):113–123. - PubMed
    1. Folch J., Lees M., Stanley G.H. Sloane. A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 1957;226(1):497–509. - PubMed