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Editorial
. 2017 Sep 12:2:70.
doi: 10.21037/tgh.2017.08.09. eCollection 2017.

Regarding the applications of fusion-fluorescence imaging using indocyanine green in laparoscopic hepatectomy

Thinzar M Lwin  1 , Robert M Hoffman  1   2 , Michael Bouvet  1
Affiliations
Editorial

Regarding the applications of fusion-fluorescence imaging using indocyanine green in laparoscopic hepatectomy

Thinzar M Lwin et al. Transl Gastroenterol Hepatol. .
No abstract available

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Conflict of interest statement

Conflicts of Interest: RM Hoffman is a non-salaried associate of AntiCancer, Inc. The other authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Fluorescence-guided surgery using a NIR-labeled anti-CEA antibody. (A) Whole‐body images before and after fluorescence-guided surgery using an anti‐CEA antibody conjugated to DyLight 650. The GFP-tagged tumor visible on the liver surface (white arrow head) was clearly detected under both GFP and anti‐CEA‐DyLight650 navigation. In contrast, the deeper tumors covered with normal tissues (yellow arrow heads) were detected only under anti‐CEA‐DyLight650 navigation. No residual tumor was detected after FGS. (B) Representative gross images of excised tumors (left panel: exposed tumor, right panel: buried tumor). Upper panels indicate bright field (BF) images, middle and lower panels indicate fluorescence images for GFP and DyLight 650, respectively. The area surrounded by a white broken line indicates the buried part of the excised tumor. Anti-CEA-DyLight650 fluorescence signal was able to penetrate normal liver tissue and visualize the buried part of the tumor, which was not detected in GFP fluorescence. Scale bars: 10 mm (A) and 2.5 mm (B). GFP, green fluorescent protein; FGS; fluorescence-guided surgery.
See this image and copyright information in PMC

Comment on

References

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