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Case Reports
. 1979 Aug;16(2):123-6.
doi: 10.1128/AAC.16.2.123.

Development of resistance to amphotericin B in Candida lusitaniae infecting a human

D Pappagianis, M S Collins, R Hector, J Remington
Case Reports

Development of resistance to amphotericin B in Candida lusitaniae infecting a human

D Pappagianis et al. Antimicrob Agents Chemother. 1979 Aug.

Abstract

Candida lusitaniae associated with infection in a patient with acute myelogenous leukemia developed resistance to amphotericin B during systemic treatment of the patient. The organism, when isolated initially, was inhibited by 0.31 mug of amphotericin B per ml in yeast nitrogen base agar, but when isolated (20 days later) just antemortem and postmortem, required 100 and 50 mug/ml, respectively, for complete inhibition at 48 h.

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