Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Aug 22;53(86):11810-11813.
doi: 10.1039/c7cc06838g.

Novel activity-based probes for N-acylethanolamine acid amidase

Rita Petracca  1 , Elisa Romeo, Marc P Baggelaar, Marta Artola, Silvia Pontis, Stefano Ponzano, Herman S Overkleeft, Mario van der Stelt, Daniele Piomelli
Affiliations

Novel activity-based probes for N-acylethanolamine acid amidase

Rita Petracca et al. Chem Commun (Camb). .

Abstract

The cysteine hydrolase, N-acylethanolamine acid amidase (NAAA) is a promising target for analgesic and anti-inflammatory drugs. Here, we describe the development of two unprecedented NAAA-reactive activity-based probes as research tools for application in the discovery of new inhibitors and for the in-depth characterization of NAAA in its cellular environment.

PubMed Disclaimer

MeSH terms

LinkOut - more resources