Evaluation of Health in Pregnancy grants in Scotland: a natural experiment using routine data
- PMID: 29035487
- Bookshelf ID: NBK458548
- DOI: 10.3310/phr05060
Evaluation of Health in Pregnancy grants in Scotland: a natural experiment using routine data
Excerpt
Background: Pregnancy and the period around birth are critical for the development and improvement of population health as well as the health of mothers and babies, with outcomes such as birthweight influencing adult health.
Objectives: We evaluated the clinical effectiveness and cost-effectiveness of the Health in Pregnancy (HiP) grants in Scotland, looking for differential outcomes when the scheme was in place, as well as before its implementation and after its withdrawal.
Design: The HiP grants were evaluated as a natural experiment using interrupted time series analysis. We had comparison groups of women who delivered before the grants were introduced and after the grants were withdrawn.
Setting: Scotland, UK.
Participants: A total of 525,400 singleton births delivered between 24 and 44 weeks in hospitals across Scotland between 1 January 2004 and 31 December 2014.
Intervention: The HiP grant was a universal, unconditional cash transfer of £190 for women in Great Britain and Northern Ireland reaching 25 weeks of pregnancy if they had sought health advice from a doctor or midwife. The grant was introduced for women with a due date on or after 6 April 2009 and subsequently withdrawn for women reaching the 25th week of pregnancy on or after 1 January 2011. The programme was paid for by Her Majesty’s Treasury.
Main outcome measures: Our primary outcome measure was birthweight. Secondary outcome measures included maternal behaviour, measures of size, measures of stage and birth outcomes.
Data sources: The data came from the Scottish maternity and neonatal database held by the Information and Services Division at the NHS National Services Scotland.
Results: There was no statistically significant effect on birthweight, with births during the intervention period being, on average, 2.3 g [95% confidence interval (CI) –1.9 to 6.6 g] lighter than would have been expected had the pre-intervention trend continued. Mean gestational age at booking (i.e. the first antenatal appointment with a health-care professional) decreased by 0.35 weeks (95% CI 0.29 to 0.41 weeks) and the odds of booking before 25 weeks increased by 10% [odds ratio (OR) 1.10, 95% CI 1.02 to 1.18] during the intervention but decreased again post intervention (OR 0.91, 95% CI 0.83 to 1.00). The odds of neonatal death increased by 84% (OR 1.84, 95% CI 1.22 to 2.78) and the odds of having an emergency caesarean section increased by 7% (OR 1.07, 95% CI 1.03 to 1.10) during the intervention period.
Conclusions: The decrease in the odds of booking before 25 weeks following withdrawal of the intervention makes it likely that the HiP grants influenced maternal health-care-seeking behaviour. It is unclear why neonatal mortality and emergency caesarean section rates increased, but plausible explanations include the effects of the swine flu outbreak in 2009 and the global financial crisis. The study is limited by its non-randomised design. Future research could assess an eligibility threshold for payment earlier than the 25th week of pregnancy.
Funding: The National Institute for Health Research Public Health Research programme. The Social and Public Health Sciences Unit is core funded by the Medical Research Council (MC_UU_12017/13) and the Scottish Government Chief Scientist Office (SPHSU13).
Copyright © Queen’s Printer and Controller of HMSO 2017. This work was produced by Leyland et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.
Sections
- Plain English summary
- Scientific summary
- Chapter 1. Introduction
- Chapter 2. Methods
- Chapter 3. Results
- Chapter 4. Discussion
- Chapter 5. Conclusions
- Acknowledgements
- References
- Appendix 1. Models specification (adjusted on gestational age at booking and maternal smoking)
- Appendix 2. Results of the analysis for the secondary outcomes using the complete cases unadjusted for gestational age at booking and maternal smoking: maternal behaviour
- Appendix 3. The results of analysis for the secondary outcomes using the complete cases unadjusted for gestational age at booking and maternal smoking: measures of size
- Appendix 4. The results of analysis for the secondary outcomes using the complete cases unadjusted for gestational age at booking and maternal smoking: measures of stage
- Appendix 5. The results of analysis for the secondary outcomes using the complete cases unadjusted for gestational age at booking and maternal smoking: birth outcomes
- Appendix 6. The results of analysis for the secondary outcomes using the complete cases and adjusting the model for gestational age at booking and maternal smoking: maternal behaviour
- Appendix 7. The results of analysis for the secondary outcomes using the complete cases and adjusting the model for gestational age at booking and maternal smoking: measures of size
- Appendix 8. The results of analysis for the secondary outcomes using the complete cases and adjusting the model for gestational age at booking and maternal smoking: measures of stage
- Appendix 9. The results of analysis for the secondary outcomes using the complete cases and adjusting the model for gestational age at booking and maternal smoking: birth outcomes
- Appendix 10. Other parameter estimates for the primary and secondary outcomes using the imputed data and unadjusted for gestational age at booking and maternal smoking: maternal behaviour
- Appendix 11. Other parameter estimates for the primary and secondary outcomes using the imputed data and unadjusted for gestational age at booking and maternal smoking: measures of size
- Appendix 12. Other parameter estimates for the primary and secondary outcomes using the imputed data and unadjusted for gestational age at booking and maternal smoking: measures of stage
- Appendix 13. Other parameter estimates for the primary and secondary outcomes using the imputed data and unadjusted for gestational age at booking and maternal smoking: birth outcomes
- Appendix 14. Variances and standard errors for the final models for each outcome
- Appendix 15. Results of the analysis for the secondary outcomes using the imputed data: subgroup of mothers living in the most deprived areas (SIMD1) – maternal behaviour
- Appendix 16. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in the most deprived areas (SIMD1) – measures of size
- Appendix 17. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in the most deprived areas (SIMD1) – measures of stage
- Appendix 18. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in the most deprived areas (SIMD1) – birth outcomes
- Appendix 19. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in SIMD2 areas – maternal behaviour
- Appendix 20. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in SIMD2 areas – measures of size
- Appendix 21. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in SIMD2 areas – measures of stage
- Appendix 22. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in SIMD2 areas – birth outcomes
- Appendix 23. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in SIMD3 areas – maternal behaviour
- Appendix 24. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in SIMD3 areas – measures of size
- Appendix 25. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in SIMD3 areas – measures of stage
- Appendix 26. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in SIMD3 areas – birth outcomes
- Appendix 27. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in SIMD4 areas – maternal behaviour
- Appendix 28. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in SIMD4 areas – measures of size
- Appendix 29. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in SIMD4 areas – measures of stage
- Appendix 30. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in SIMD4 areas – birth outcomes
- Appendix 31. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in the least deprived areas – maternal behaviour
- Appendix 32. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in the least deprived areas – measures of size
- Appendix 33. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in the least deprived areas – measures of stage
- Appendix 34. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in the least deprived areas – birth outcomes
- Appendix 35. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers with diabetes mellitus (before or during pregnancy) – maternal behaviour
- Appendix 36. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers with diabetes mellitus (before or during pregnancy) – measures of size
- Appendix 37. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers with diabetes mellitus (before or during pregnancy) – measures of stage
- Appendix 38. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers with diabetes mellitus (before or during pregnancy) – birth outcomes
- Appendix 39. Results of analysis for the secondary outcomes using the imputed data: subgroup of obese mothers (BMI ≥ 35 kg/m2) – maternal behaviour
- Appendix 40. Results of analysis for the secondary outcomes using the imputed data: subgroup of obese mothers (BMI ≥ 35 kg/m2) – measures of size
- Appendix 41. Results of analysis for the secondary outcomes using the imputed data: subgroup of obese mothers (BMI ≥ 35 kg/m2) – measures of stage
- Appendix 42. Results of analysis for the secondary outcomes using the imputed data: subgroup of obese mothers (BMI ≥ 35 kg/m2) – birth outcomes
- Appendix 43. Results of analysis for the secondary outcomes using the imputed data: subgroup of lone mothers – maternal behaviour
- Appendix 44. Results of analysis for the secondary outcomes using the imputed data: subgroup of lone mothers – measures of size
- Appendix 45. Results of analysis for the secondary outcomes using the imputed data: subgroup of lone mothers – measures of stage
- Appendix 46. Results of analysis for the secondary outcomes using the imputed data: subgroup of lone mothers – birth outcomes
- Appendix 47. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in households where the head is in the group of working-class people – maternal behaviour
- Appendix 48. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in households where the head is in the group of working-class people – measures of size
- Appendix 49. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in households where the head is in the group of working-class people – measures of stage
- Appendix 50. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in households where the head is in the group of working-class people – birth outcomes
- Appendix 51. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in households where the head is in the group of people who have never worked – maternal behaviour
- Appendix 52. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in households where the head is in the group of people who have never worked – measures of size
- Appendix 53. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in households where the head is in the group of people who have never worked – measures of stage
- Appendix 54. Results of analysis for the secondary outcomes using the imputed data: subgroup of mothers living in households where the head is in the group of people who have never worked – birth outcomes
- Appendix 55. Results of analysis for the secondary outcomes using the imputed data: subgroup of teen mothers (< 20 years old) – maternal behaviour
- Appendix 56. Results of analysis for the secondary outcomes using the imputed data: subgroup of teen mothers (< 20 years old) – measures of size
- Appendix 57. Results of analysis for the secondary outcomes using the imputed data: subgroup of teen mothers (< 20 years old) – measures of stage
- Appendix 58. Results of analysis for the secondary outcomes using the imputed data: subgroup of teen mothers (< 20 years old) – birth outcomes
- Appendix 59. Results of analysis for the secondary outcomes using the imputed data: subgroup of non-white mothers – maternal behaviour
- Appendix 60. Results of analysis for the secondary outcomes using the imputed data: subgroup of non-white mothers – measures of size
- Appendix 61. Results of analysis for the secondary outcomes using the imputed data: subgroup of non-white mothers – measures of stage
- Appendix 62. Results of analysis for the secondary outcomes using the imputed data: subgroup of non-white mothers – birth outcomes
- Appendix 63. Results of the main analysis for the secondary outcomes adjusted for ethnicity and using the complete cases: maternal behaviour
- Appendix 64. Results of the main analysis for the primary and secondary outcomes adjusted for ethnicity and using the complete cases: measures of size
- Appendix 65. Results of the main analysis for the secondary outcomes adjusted for ethnicity and using the complete cases: measures of stage
- Appendix 66. Results of the main analysis for the secondary outcomes adjusted for ethnicity and using the complete cases: birth outcomes
- Appendix 67. Results of analysis for the secondary outcomes using the imputed data: subgroup of nulliparous mothers – maternal behaviour
- Appendix 68. Results of analysis for the primary and secondary outcomes using the imputed data: subgroup of nulliparous mothers – measures of size
- Appendix 69. Results of analysis for the secondary outcomes using the imputed data: subgroup of nulliparous mothers – measures of stage
- Appendix 70. Results of analysis for the secondary outcomes using the imputed data: subgroup of nulliparous mothers – birth outcomes
- Appendix 71. Impact of restricting the pre-intervention period to the period after the smoking ban: maternal behaviour
- Appendix 72. Impact of restricting the pre-intervention period to the period after the smoking ban: measures of size
- Appendix 73. Impact of restricting the pre-intervention period to the period after the smoking ban: measures of stage
- Appendix 74. Impact of restricting the pre-intervention period to the period after the smoking ban: birth outcomes
- Appendix 75. Impact of moving the real Health in Pregnancy grant period: restriction to 18 months
- Appendix 76. Impact of moving the real Health in Pregnancy grant period: extension to 30 months
- Appendix 77. Impact of moving the real Health in Pregnancy grant period: exclusion of births that occurred during the 2009 swine flu outbreak
- Appendix 78. Impact of moving the start of the intervention period to one year before the real Health in Pregnancy grant period: 24-month intervention period
- Appendix 79. Impact of moving the start of the intervention period to 1 year before the real Health in Pregnancy grant period: 18-month intervention period
- Appendix 80. Impact of moving the start of the intervention period to 1 year before the real Health in Pregnancy grant period: 30-month intervention period
- Appendix 81. Impact of moving the start of the intervention period to 6 months before the real Health in Pregnancy grant period: 24-month intervention period
- Appendix 82. Impact of moving the start of the intervention period to 6 months before the real Health in Pregnancy grant period: 18-month intervention period
- Appendix 83. Impact of moving the start of the intervention period to 6 months before the real Health in Pregnancy grant period: 30-month intervention period
- Appendix 84. Impact of moving the start of the intervention period to 6 months after the real Health in Pregnancy grant period: 24-month intervention period
- Appendix 85. Impact of moving the start of the intervention period to 6 months after the real Health in Pregnancy grant period: 18-month intervention period
- Appendix 86. Impact of moving the start of the intervention period to 6 months after the real Health in Pregnancy grant period: 30-month intervention period
- Appendix 87. Impact of moving the start of the intervention period to 1 year after the real Health in Pregnancy grant period: 24-month intervention period
- Appendix 88. Impact of moving the start of the intervention period to 1 year after the real Health in Pregnancy grant period: 18-month intervention period
- Appendix 89. Impact of moving the start of the intervention period to 1 year after the real Health in Pregnancy grant period: 30-month intervention period
- Appendix 90. STrengthening the Reporting of OBservational studies in Epidemiology statement for reporting of observational studies
- List of abbreviations
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