Effects of hexavalent chromium on trout mitochondria
- PMID: 2903588
- DOI: 10.1016/0378-4274(88)90131-2
Effects of hexavalent chromium on trout mitochondria
Abstract
Trout liver mitochondria were incubated in the presence of micromolar concentration of potassium dichromate (Cr(VI)) under several experimental conditions. Cr(VI) strongly inhibited both state 3 and state 4 of respiration supplemented by NAD-linked substrates; it also slightly affected the respiration of FAD-linked substrates. Evidence is provided that the respiratory inhibition induced by dichromate is partially coupled to the Cr(VI) reduction mechanism occurring in mitochondria.
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