Closing the Genotype-Phenotype Loop for Precision Medicine
- PMID: 29038206
- PMCID: PMC6540750
- DOI: 10.1161/CIRCULATIONAHA.117.030831
Closing the Genotype-Phenotype Loop for Precision Medicine
Keywords: Editorials; cardiomyopathies; cardiovascular diseases; cell biology; genomics; phenotype; precision medicine.
Conflict of interest statement
Conflict of Interest Disclosures: None.
Comment on
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Experimental Modeling Supports a Role for MyBP-HL as a Novel Myofilament Component in Arrhythmia and Dilated Cardiomyopathy.Circulation. 2017 Oct 17;136(16):1477-1491. doi: 10.1161/CIRCULATIONAHA.117.028585. Epub 2017 Aug 4. Circulation. 2017. PMID: 28778945 Free PMC article.
References
-
- Baslan T, Hicks J. Unravelling biology and shifting paradigms in cancer with single-cell sequencing. Nat Rev Cancer. 2017;17:557–569. - PubMed
-
- Schreiber SL, Kotz JD, Li M, Aubé J, Austin CP, Reed JC, Rosen H, White EL, Sklar LA, Lindsley CW, Alexander BR, Bittker JA, Clemons PA, de Souza A, Foley MA, Palmer M, Shamji AF, Wawer MJ, McManus O, Wu M, Zou B, Yu H, Golden JE, Schoenen FJ, Simeonov A, Jadhav A, Jackson MR, Pinkerton AB, Chung TD, Griffin PR, Cravatt BF, Hodder PS, Roush WR, Roberts E, Chung DH, Jonsson CB, Noah JW, Severson WE, Ananthan S, Edwards B, Oprea TI, Conn PJ, Hopkins CR, Wood MR, Stauffer SR, Emmitte KA; NIH Molecular Libraries Project Team. Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes. Cell. 2015;161:1252–1265. - PMC - PubMed
-
- National Cancer Policy Forum BoHCS, Health and Medicine DIvision, National Academies of Sciences, Engineeering and Medicine. The Drug Development Paradigm in Oncology: Proceedings of a Workshop. Washington (DC)2017. National Academies Press. - PubMed
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