Research, regulatory, and clinical decision-making: the importance of scientific integrity

Affiliations

¹ Collaboration for Research Integrity and Transparency (CRIT), Yale Law School, 157 Church Street, 17th Floor, Suite 1, New Haven, CT 06510-2100, USA; Center for Outcomes Research and Evaluation (CORE), Yale-New Haven Hospital, 1 Church Street # 200, New Haven, CT 06510-2100, USA. Electronic address: joshua.wallach@yale.edu.
² Collaboration for Research Integrity and Transparency (CRIT), Yale Law School, 157 Church Street, 17th Floor, Suite 1, New Haven, CT 06510-2100, USA; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, 60 College Street, P.O. Box 208034, New Haven, CT 06520-8034, USA; Yale Law School, Yale University, 127 Wall Street, New Haven, CT 06511, USA.
³ Collaboration for Research Integrity and Transparency (CRIT), Yale Law School, 157 Church Street, 17th Floor, Suite 1, New Haven, CT 06510-2100, USA; Center for Outcomes Research and Evaluation (CORE), Yale-New Haven Hospital, 1 Church Street # 200, New Haven, CT 06510-2100, USA; Section of General Medicine, Department of Internal Medicine, Yale School of Medicine, P.O. Box 208093, New Haven, CT 06520-8093, USA; Department of Health Policy and Management, Yale School of Public Health, 60 College Street, New Haven, CT 06510-2100, USA.

Joshua D Wallach et al. J Clin Epidemiol. 2018 Jan.

. 2018 Jan:93:88-93.

doi: 10.1016/j.jclinepi.2017.08.021. Epub 2017 Oct 16.

¹ Collaboration for Research Integrity and Transparency (CRIT), Yale Law School, 157 Church Street, 17th Floor, Suite 1, New Haven, CT 06510-2100, USA; Center for Outcomes Research and Evaluation (CORE), Yale-New Haven Hospital, 1 Church Street # 200, New Haven, CT 06510-2100, USA. Electronic address: joshua.wallach@yale.edu.
² Collaboration for Research Integrity and Transparency (CRIT), Yale Law School, 157 Church Street, 17th Floor, Suite 1, New Haven, CT 06510-2100, USA; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, 60 College Street, P.O. Box 208034, New Haven, CT 06520-8034, USA; Yale Law School, Yale University, 127 Wall Street, New Haven, CT 06511, USA.
³ Collaboration for Research Integrity and Transparency (CRIT), Yale Law School, 157 Church Street, 17th Floor, Suite 1, New Haven, CT 06510-2100, USA; Center for Outcomes Research and Evaluation (CORE), Yale-New Haven Hospital, 1 Church Street # 200, New Haven, CT 06510-2100, USA; Section of General Medicine, Department of Internal Medicine, Yale School of Medicine, P.O. Box 208093, New Haven, CT 06520-8093, USA; Department of Health Policy and Management, Yale School of Public Health, 60 College Street, New Haven, CT 06510-2100, USA.

No abstract available

Keywords: Data sharing; Integrity; Misconduct; Reproducibility; Transparency.

Comment in

Fostering responsible research practices is a shared responsibility of multiple stakeholders.
Bouter LM. Bouter LM. J Clin Epidemiol. 2018 Apr;96:143-146. doi: 10.1016/j.jclinepi.2017.12.016. Epub 2017 Dec 21. J Clin Epidemiol. 2018. PMID: 29275217 No abstract available.
Preregistration and publication of nonregulated intervention trials are here to stay (letter commenting Wallach et al 2018, 93, 88-93).
Dal-Ré R. Dal-Ré R. J Clin Epidemiol. 2018 Jul;99:167-168. doi: 10.1016/j.jclinepi.2018.02.014. Epub 2018 Feb 23. J Clin Epidemiol. 2018. PMID: 29481856 No abstract available.

Reproducible research practices, transparency, and open access data in the biomedical literature, 2015-2017.
Wallach JD, Boyack KW, Ioannidis JPA. Wallach JD, et al. PLoS Biol. 2018 Nov 20;16(11):e2006930. doi: 10.1371/journal.pbio.2006930. eCollection 2018 Nov. PLoS Biol. 2018. PMID: 30457984 Free PMC article.
Consistency between trials presented at conferences, their subsequent publications and press releases.
Rowhani-Farid A, Hong K, Grewal M, Reynolds J, Zhang AD, Wallach JD, Ross JS. Rowhani-Farid A, et al. BMJ Evid Based Med. 2023 Apr;28(2):95-102. doi: 10.1136/bmjebm-2022-111989. Epub 2022 Nov 10. BMJ Evid Based Med. 2023. PMID: 36357160 Free PMC article.
Risk of bias in exercise science: A systematic review of 340 studies.
Preobrazenski N, McCaig A, Turner A, Kushner M, Pacitti L, Mendolia P, MacDonald B, Storoschuk K, Bouck T, Zaza Y, Lu S, Gurd BJ. Preobrazenski N, et al. iScience. 2024 Jan 26;27(3):109010. doi: 10.1016/j.isci.2024.109010. eCollection 2024 Mar 15. iScience. 2024. PMID: 38405604 Free PMC article.
Estimating the Prevalence of Transparency and Reproducibility-Related Research Practices in Psychology (2014-2017).
Hardwicke TE, Thibault RT, Kosie JE, Wallach JD, Kidwell MC, Ioannidis JPA. Hardwicke TE, et al. Perspect Psychol Sci. 2022 Jan;17(1):239-251. doi: 10.1177/1745691620979806. Epub 2021 Mar 8. Perspect Psychol Sci. 2022. PMID: 33682488 Free PMC article.