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Meta-Analysis
. 2017 Oct;110(10):404-410.
doi: 10.1177/0141076817731904.

Cognitive behavioural therapy halves the risk of repeated suicide attempts: systematic review

Peter C Gøtzsche  1 , Pernille K Gøtzsche  1
Affiliations
Meta-Analysis

Cognitive behavioural therapy halves the risk of repeated suicide attempts: systematic review

Peter C Gøtzsche et al. J R Soc Med. 2017 Oct.

Abstract

Objective To study whether cognitive behavioural therapy decreases suicide attempts in people with previous suicide attempts. Design Systematic review and meta-analysis. Setting Randomised trials that compare cognitive behavioural therapy with treatment as usual. Participants Patients who had engaged in any type of suicide attempt in the six months prior to trial entry resulting in presentation to clinical services. Main outcome measure Suicide attempt. Results We included ten trials, eight from Cochrane reviews and two from our updated searches (1241 patients, 219 of whom had at least one new suicide attempt). Cognitive behavioural therapy compared to treatment as usual reduced the risk of a new suicide attempt; risk ratio 0.47; 95% confidence interval 0.30-0.73; p = 0.0009; I2 = 57%. Only seven suicides were reported (3 versus 4). One trial had an unusually large effect; if this trial is excluded, the risk ratio becomes 0.61 (0.46-0.80) and the heterogeneity in the results disappears (I2 = 0%). Conclusions Cognitive behavioural therapy reduces not only repeated self-harm but also repeated suicide attempts. It should be the preferred treatment for all patients with depression.

Keywords: Clinical; psychiatry; psychotherapy; suicide.

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Figures

Figure 1.
Figure 1.
Meta-analysis of suicide attempts. CBT: cognitive behavioural therapy; TAU: treatment as usual.
See this image and copyright information in PMC

References

    1. Hawton K, Witt KG, Taylor Salisbury TL, Arensman E, Gunnell D, Hazell P, et al. Psychosocial interventions for self-harm in adults. Cochrane Database Syst Rev 2016; 5: CD012189–CD012189. - PMC - PubMed
    1. Owens D, Horrocks J, House A. Fatal and non-fatal repetition of self-harm. Systematic review. Br J Psychiatry 2002; 181: 193–199. - PubMed
    1. Hawton K, Witt KG, Taylor Salisbury TL, Arensman E, Gunnell D, Townsend E, et al. Interventions for self-harm in children and adolescents. Cochrane Database Syst Rev 2015; 12: CD012013–CD012013. - PMC - PubMed
    1. Brown GK, Ten Have T, Henriques GR, Xie SX, Hollander JE, Beck AT. Cognitive therapy for the prevention of suicide attempts: a randomized controlled trial. JAMA 2005; 294: 563–570. - PubMed
    1. Dubois L, Walter M, Bleton L, Genest P, Lemonnier E, Lachevre G. Evaluation comparative et prospective d’un protocole de prise en charge specifique de jeunes suicidants: analyse du diagnostic psychiatrique initial, de l’observance therapeutique et du taux de recidive a un an (resultats preliminaires)]. Ann Medico-Psychol 1999; 157: 557–561.

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