Comparative Study
doi: 10.1038/336551a0.
A human lymphoid-specific transcription factor that activates immunoglobulin genes is a homoeobox protein
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- PMID: 2904654
- DOI: 10.1038/336551a0
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Comparative Study
A human lymphoid-specific transcription factor that activates immunoglobulin genes is a homoeobox protein
Nature.
.
Abstract
The human lymphoid-specific transcription factor OTF-2 contains a homoeodomain that is required for DNA binding and binds specifically to DNA elements that are recognized by Drosophila homoeodomain proteins, suggesting coevolutionary relationships between mammalian and invertebrate homoeodomain proteins and their DNA recognition elements.
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