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. 2017 Nov;23(11):1883-1886.
doi: 10.3201/eid2311.161443.

Virulence of Japanese Encephalitis Virus Genotypes I and III, Taiwan

Yi-Chin Fan, Jen-Wei Lin, Shu-Ying Liao, Jo-Mei Chen, Yi-Ying Chen, Hsien-Chung Chiu, Chen-Chang Shih, Chi-Ming Chen, Ruey-Yi Chang, Chwan-Chuen King, Wei-June Chen, Yi-Ting Ko, Chao-Chin Chang, Shyan-Song Chiou

Virulence of Japanese Encephalitis Virus Genotypes I and III, Taiwan

Yi-Chin Fan et al. Emerg Infect Dis. 2017 Nov.

Abstract

The virulence of genotype I (GI) Japanese encephalitis virus (JEV) is under debate. We investigated differences in the virulence of GI and GIII JEV by calculating asymptomatic ratios based on serologic studies during GI- and GIII-JEV endemic periods. The results suggested equal virulence of GI and GIII JEV among humans.

Keywords: Asia; GI JEV; GIII JEV; Japanese encephalitis virus; Taiwan; Western Pacific; asymptomatic ratio; flavivirus; genotype; meningitis/encephalitis; mosquitoborne; vector-borne infections; virulence; viruses.

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Figures

Figure
Figure
JEV genotype-specific asymptomatic ratios for 8 serum panels collected during the GIII- and GI-endemic periods (1994–2000 and 2010–2012) in Taiwan. The adjusted asymptomatic ratios estimated from genotype-representing populations were included to calculate JEV genotype-specific asymptomatic ratios. Horizontal lines indicate mean; error bars indicate SEM. JEV, Japanese encephalitis virus.
See this image and copyright information in PMC

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