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. 2017 Oct 17;318(15):1498-1500.
doi: 10.1001/jama.2017.11483.

Acute Zika Virus Infection as a Risk Factor for Guillain-Barré Syndrome in Puerto Rico

Emilio Dirlikov  1 , Nicole A Medina  2 , Chelsea G Major  3 , Jorge L Munoz-Jordan  2 , Carlos A Luciano  4 , Brenda Rivera-Garcia  5 , Tyler M Sharp  2
Affiliations

Acute Zika Virus Infection as a Risk Factor for Guillain-Barré Syndrome in Puerto Rico

Emilio Dirlikov et al. JAMA. .

Abstract

This case-control study conducted during the Zika virus epidemic in Puerto Rico estimates the association between preceding Zika virus infection and subsequent Guillain-Barré syndrome.

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Conflict of interest statement

Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Luciano reported grant funding from the University of Puerto Rico Medical Sciences. No other disclosures were reported.

References

    1. Willison HJ, Jacobs BC, van Doorn PA. Guillain-Barré syndrome. Lancet. 2016;388(10045):717-727. - PubMed
    1. Dos Santos T, Rodriguez A, Almiron M, et al. Zika virus and the Guillain-Barré syndrome—case series from seven countries. N Engl J Med. 2016;375(16):1598-1601. - PubMed
    1. Petersen LR, Jamieson DJ, Honein MA. Zika virus. N Engl J Med. 2016;375(3):294-295. - PubMed
    1. Sejvar JJ, Kohl KS, Gidudu J, et al. Guillain-Barré syndrome and Fisher syndrome. Vaccine. 2011;29(3):599-612. - PubMed
    1. Cao-Lormeau VM, Blake A, Mons S, et al. Guillain-Barré syndrome outbreak associated with Zika virus infection in French Polynesia. Lancet. 2016;387(10027):1531-1539. - PMC - PubMed

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