The Multi-Faceted Relationship between White Matter Lesions and Late-Life Depression
- PMID: 29050911
- PMCID: PMC10833147
- DOI: 10.1016/j.jagp.2017.09.017
The Multi-Faceted Relationship between White Matter Lesions and Late-Life Depression
Comment on
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White Matter Lesions are Associated with Specific Depressive Symptom Trajectories among Incident Depression and Dementia Populations: Three-City Dijon MRI Study.Am J Geriatr Psychiatry. 2017 Dec;25(12):1311-1321. doi: 10.1016/j.jagp.2017.06.003. Epub 2017 Jul 5. Am J Geriatr Psychiatry. 2017. PMID: 28688824
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References
-
- Alexopoulos GS, Meyers BS, Young RC, Campbell S, Silbersweig D, and Charlson M (1997). “Vascular Depression” Hypothesis. Arch Gen Psychiatry 54, 915–922. - PubMed
-
- Thomas AJ, Perry R, Kalaria RN, Oakley A, McMeekin W, and O’BRIEN JT (2003). Neuropathological evidence for ischemia in the white matter of the dorsolateral prefrontal cortex in late-life depression. International Journal of Geriatric Psychiatry 18, 7–13. - PubMed
-
- Greenstein AS, Paranthaman R, Burns A, Jackson A, Malik RA, Baldwin RC, and Heagerty AM (2010). Cerebrovascular damage in late-life depression is associated with structural and functional abnormalities of subcutaneous small arteries. Hypertension 56, 734–740. - PubMed
-
- Krishnan KRR, Hays JC, and Blazer DG (1997). MRI-defined vascular depression. American Journal of Psychiatry 154, 497–501. - PubMed
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