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Review
. 2018 Jan;27(1):3-10.
doi: 10.1158/1055-9965.EPI-17-0420. Epub 2017 Oct 20.

Breast Cancer in Latinas: A Focus on Intrinsic Subtypes Distribution

Silvia J Serrano-Gómez  1 , Laura Fejerman  2 , Jovanny Zabaleta  3   4
Affiliations
Review

Breast Cancer in Latinas: A Focus on Intrinsic Subtypes Distribution

Silvia J Serrano-Gómez et al. Cancer Epidemiol Biomarkers Prev. 2018 Jan.

Abstract

Breast cancer is the most frequent cancer in women worldwide. It is classified into intrinsic subtypes characterized by different molecular profiles and prognosis. The prevalence of the different intrinsic subtypes varies between population groups. IHC surrogates based on the expression of the estrogen receptor, progesterone receptor, and HER2 have been widely used to study the distribution of intrinsic subtypes in non-Hispanic whites and African Americans, but data are limited for Hispanic/Latina women. Similarly, most studies analyzing gene expression profiles only include women of European descent. This review focuses on studies that describe the distribution of breast cancer subtypes in Hispanic/Latina women and highlights the need for more research in this population. Cancer Epidemiol Biomarkers Prev; 27(1); 3-10. ©2017 AACR.

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