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. 2017 Jul:2017:161-164.
doi: 10.1109/EMBC.2017.8036787.

Central sulcus development in early childhood

Niharika Gajawelli, Sean Deoni, Holly Dirks, Douglas Dean, Jonathan O'Muircheartaigh, Yalin Wang, Marvin D Nelson, Olivier Coulon, Natasha Lepore

Central sulcus development in early childhood

Niharika Gajawelli et al. Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul.

Abstract

Mapping out the development of the brain in early childhood is a critical part of understanding neurological disorders. The brain grows rapidly in early life, reaching 95% of the final volume by age 6. A normative atlas containing structural parameters that indicate development would be a powerful tool in understanding the progression of neurological diseases. Although some studies have begun exploring cortical development in pediatric imaging, sulci have not been examined extensively. Here, we study the changes in the Central Sulcus (CS), which is one of the earliest sulci to develop from the fetal stage, at early developmental age 1-3 years old using high resolution magnetic resonance images. Parameterization of the central sulcus was performed and results show us that the CS change corresponds to the development of the mouth and tongue regions.

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Figures

Figure 1
Figure 1
An example of the central sulcus after parameterization using Brainvisa.
Figure 2
Figure 2
The sulcal depth profiles of the left and right CS for 1, 2, and 3 year old groups. Top and Bottom: Left CS and right CS depth curves respectively.
Figure 3
Figure 3
Linear regression results showing the slope of change for all the sulcal positions in the CS in the left and right hemispheres. Top: Left hemisphere, Bottom: Right hemisphere. The red circles indicate the region of selected ROIs. The left circles indicate the trunk/neck region and the right circle indicate the mouth and tongue area.
See this image and copyright information in PMC

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