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Case Reports
. 2017 Sep 1;52(3):165-168.
doi: 10.5152/TurkPediatriArs.2017.2931. eCollection 2017 Sep.

A congenital cranial dysinnervation disorder: Möbius' syndrome

Hatice Mutlu Albayrak  1 , Nuriye Tarakçı  2 , Hüseyin Altunhan  2 , Rahmi Örs  2 , Hüseyin Çaksen  3
Affiliations
Case Reports

A congenital cranial dysinnervation disorder: Möbius' syndrome

Hatice Mutlu Albayrak et al. Turk Pediatri Ars. .

Erratum in

  • Erratum.
    [No authors listed] [No authors listed] Turk Pediatri Ars. 2017 Dec 1;52(4):246. doi: 10.5152/TurkPediatriArs.2017.151117. eCollection 2017 Dec. Turk Pediatri Ars. 2017. PMID: 29485139 Free PMC article.

Abstract

Möbius' syndrome, also known as Möbius' sequence, is a nonprogressive cranial dysinnervation disorder characterized by congenital facial and abducens nerve paralysis. Here, we report a 5-day-old girl who was conceived after in vitro fertilization with poor suck and facial paralysis. She had bilaterally ptosis and lateral gaze limitation, left-sided deviation of the tongue, dysmorphic face, hypoplastic fingers and finger nails on the left hand, and was diagnosed as having Möbius' syndrome. Involvement of other cranial nerves such as three, four, five, nine, 9 and 12, and limb malformations may accompany this syndrome. However, several factors have been proposed for the etiology, some rare cases have also been reported with artificial reproductive technologies. Feeding difficulties and aspiration are the main problems encountered in infancy. The other cranial nerves should be examined further in newborns who present with congenital facial palsy, and other cranial dysinnervation disorders should be considered in the differential diagnosis.

Keywords: Artificial reproductive technologies; Möbius’ syndrome; congenital facial paralysis.

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Conflict of interest statement

Conflict of Interest: No conflict of interest was declared by the authors.

Figures

Picture 1
Picture 1
Convergent strabismus and right facial palsy, dysmorphic facial appearance
Picture 2
Picture 2
Unilateral tongue paralysis
Picture 3. a–c
Picture 3. a–c
Right hand with normal appearance (a), Pen-point appearance of the fingers in the right hand (b), left hand antero-posterior graphy revealing hypoplasia in the distal phalanges (c)
See this image and copyright information in PMC

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