Mitotic Chromosomes: Not So Silent After All
- PMID: 29065303
- DOI: 10.1016/j.devcel.2017.10.002
Mitotic Chromosomes: Not So Silent After All
Abstract
Mitotic chromosome condensation is believed to be incompatible with transcription. Palozola et al. (2017) now report in Science that a transcription program is maintained during mitosis and that transcriptional re-activation at mitotic exit is geared to support cell growth rather than cell identity.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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Mitotic transcription and waves of gene reactivation during mitotic exit.Science. 2017 Oct 6;358(6359):119-122. doi: 10.1126/science.aal4671. Epub 2017 Sep 14. Science. 2017. PMID: 28912132 Free PMC article.
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