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. 2017 Oct 24;15(1):211.
doi: 10.1186/s12955-017-0790-x.

Impact of 6 months of treatment with intragastric balloon on body fat and quality of life in obese individuals with metabolic syndrome

Erika Paniago Guedes  1   2 , Eduardo Madeira  3   4 , Thiago Thomaz Mafort  5 , Miguel Madeira  4 , Rodrigo Oliveira Moreira  6   4 , Laura Maria Carvalho de Mendonça  7 , Amélio Fernando de Godoy-Matos  6 , Agnaldo José Lopes  5 , Maria Lucia Fleiuss Farias  4
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Impact of 6 months of treatment with intragastric balloon on body fat and quality of life in obese individuals with metabolic syndrome

Erika Paniago Guedes et al. Health Qual Life Outcomes. .

Abstract

Background: Obesity is a worldwide public health issue with a negative impact on quality of life. Different weight loss interventions have demonstrated improvements in quality of life. The aim of this study was to investigate the effect of 6 months of treatment with an intragastric balloon (IGB) on health-related quality of life (HRQOL) and its relation to changes in body fat in obese individuals with metabolic syndrome (MS).

Methods: Fifty obese patients with MS aged 18-50 were selected for treatment with IGB for 6 months. Body fat was assessed with anthropometric measures and dual-energy X-ray absorptiometry (DXA) at baseline and after removal of the IGB. HRQOL was evaluated with the short form of the World Health Organization Quality of Life (WHOQOL-BREF) at baseline and soon after removal of the IGB.

Results: Thirty-nine patients completed the study. After 6 months, there was a significant improvement in quality of life (p = 0.0009) and health (p < 0.0001) perceptions, and in the Physical (p = 0.001), Psychological (p = 0.031), and Environmental domains (p = 0.0071). Anthropometric measures and total fat determined by DXA were directly and significantly related to an improvement in general aspects of quality of life. The decrease in the percentage of total fat was the parameter that better correlated with improvements in quality of life perception after regression (p = 0.032).

Conclusions: In obese individuals with MS, weight loss parameters were associated with short-term improvements in HRQOL after 6 months of treatment with IGB. However, only total fat was independently related to HRQOL perception.

Trial registration: ClinicalTrials.gov NCT01598233 .

Keywords: Body composition; Health-related quality of life; Intragastric balloon; Obesity.

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Conflict of interest statement

Ethics approval and consent to participate

This study was approved by the Ethics Committee of the State Institute of Diabetes and Endocrinology of Rio de Janeiro and was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. Written informed consent was obtained from each participant included in the study.

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

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Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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References

    1. Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the global burden of disease study 2013. Lancet. 2014;384:766–781. doi: 10.1016/S0140-6736(14)60460-8. - DOI - PMC - PubMed
    1. Guh DP, Zhang W, Bansback N, Amarsi Z, Birmingham CL, Anis AH. The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis. BMC Public Health. 2009;9:88. doi: 10.1186/1471-2458-9-88. - DOI - PMC - PubMed
    1. Apovian CM. Obesity: definition, comorbidities, causes, and burden. Am J Maneg Care. 2016;22(7 Suppl):s176–s185. - PubMed
    1. Global BMI Mortality Collaboration Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents. Lancet. 2016;388(10046):776–786. doi: 10.1016/S0140-6736(16)30175-1. - DOI - PMC - PubMed
    1. Kritchevsky SB, Beavers KM, Miller ME, Shea MK, Houston DK, Kitzman DW, Nicklas BJ. Intentional weight loss and all-cause mortality: a meta-analysis of randomized clinical trials. PLoS One. 2015;10(3):e0121993. doi: 10.1371/journal.pone.0121993. - DOI - PMC - PubMed

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