Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2018 Aug;67(8):1558-1559.
doi: 10.1136/gutjnl-2017-315281. Epub 2017 Oct 24.

Low eukaryotic viral richness is associated with faecal microbiota transplantation success in patients with UC

Nádia Conceição-Neto  1   2 , Ward Deboutte  1 , Tim Dierckx  2 , Kathleen Machiels  3 , Jun Wang  4   5 , Kwe Claude Yinda  1   2 , Piet Maes  2 , Marc Van Ranst  2 , Marie Joossens  4   5 , Jeroen Raes  4   5 , Séverine Vermeire  3 , Jelle Matthijnssens  1
Affiliations
Comment

Low eukaryotic viral richness is associated with faecal microbiota transplantation success in patients with UC

Nádia Conceição-Neto et al. Gut. 2018 Aug.
No abstract available

Keywords: intestinal microbiology; ulcerative colitis.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Overview of the sample collection from patients and donors and their respective remission periods. For the partial responder (patient 4), samples from the remission period were considered as responder in the analyses. Patient 3 vomited after the first FMT, leading to bilateral aspiration and bilateral pneumonia for which the patient was treated for 14 days with broad-spectrum antibiotics. On patient’s request, a second FMT was administered 8 weeks later, and the patient has been in clinical remission ever since. FMT, faecal microbiota transplantation.
Figure 2
Figure 2
(A) Phageome and (B) eukaryotic virome richness comparisons between: (1) healthy donor and patients; (2) responders and non-responders at baseline and (3) donors of responders and non-responders at baseline.
See this image and copyright information in PMC

Comment on

References

    1. Zuo T, Wong SH, Lam K, et al. . Bacteriophage transfer during faecal microbiota transplantation in Clostridium difficile infection is associated with treatment outcome. Gut 2017. [Epub ahead of print: 24 May 2017] 10.1136/gutjnl-2017-313952 - DOI - PMC - PubMed
    1. van Nood E, Vrieze A, Nieuwdorp M, et al. . Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med 2013;368:407–15. 10.1056/NEJMoa1205037 - DOI - PubMed
    1. Austin M, Mellow M, Tierney WM. Fecal microbiota transplantation in the treatment of Clostridium difficile infections. Am J Med 2014;127:479–83. 10.1016/j.amjmed.2014.02.017 - DOI - PubMed
    1. Cammarota G, Ianiro G, Tilg H, et al. . European consensus conference on faecal microbiota transplantation in clinical practice. Gut 2017;66:569–80. 10.1136/gutjnl-2016-313017 - DOI - PMC - PubMed
    1. Vermeire S, Joossens M, Verbeke K, et al. . Donor species richness determines faecal microbiota transplantation success in inflammatory Bowel disease. J Crohns Colitis 2016;10:387–94. 10.1093/ecco-jcc/jjv203 - DOI - PMC - PubMed

Publication types