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. 2017 Dec;48(6):686-690.
doi: 10.1111/age.12609. Epub 2017 Oct 27.

Genome-wide association analysis of residual feed intake in Junmu No. 1 White pigs

C Bai  1 , Y Pan  1 , D Wang  1 , F Cai  1 , S Yan  1 , Z Zhao  1 , B Sun  1
Affiliations

Genome-wide association analysis of residual feed intake in Junmu No. 1 White pigs

C Bai et al. Anim Genet. 2017 Dec.

Abstract

Residual feed intake (RFI) is a measure of feed efficiency. Pigs with low RFI have reduced feed costs without compromising their growth. For marker-assisted selection, it is helpful to identify genes or genetic markers associated with RFI in animals with improved feed efficiency at an early age. Using Illumina's PorcineSNP60 BeadChip, we performed a pilot genome-wide association study of 217 Junmu No. 1 white male pigs phenotyped for RFI. Two-step and one-step methods were used separately to identify associated SNPs. Both methods obtained similar results. Twelve SNPs were identified as significantly associated with RFI at a Bonferroni adjusted P-level < 9.7 × 10-7 , and 204 were found to have suggestive (moderately significant) association with RFI at P < 5 × 10-5 . NMBR, KCTD16, ASGR1, PRKCQ, PITRM1, TIAM1 and RND3 were identified as candidate genes for RFI.

Keywords: QTL; SNP; feed efficiency; immunity.

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