Biomarkers Associated with the Outcome of Traumatic Brain Injury Patients
- PMID: 29076989
- PMCID: PMC5704149
- DOI: 10.3390/brainsci7110142
Biomarkers Associated with the Outcome of Traumatic Brain Injury Patients
Abstract
This review focuses on biomarkers associated with the outcome of traumatic brain injury (TBI) patients, such as caspase-3; total antioxidant capacity; melatonin; S100B protein; glial fibrillary acidic protein (GFAP); glutamate; lactate; brain-derived neurotrophic factor (BDNF); substance P; neuron-specific enolase (NSE); ubiquitin carboxy-terminal hydrolase L-1 (UCH-L1); tau; decanoic acid; and octanoic acid.
Keywords: biomarkers; caspase-3; malondialdehyde; melatonin; mortality; prognosis; substance P; total antioxidant capacity; traumatic brain injury.
Conflict of interest statement
The author declares no conflict of interest.
References
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- Brain Trauma Foundation. American Association of Neurological Surgeons. Congress of Neurological Surgeons Guidelines for the management of severe traumatic brain injury. J. Neurotrauma. 2007;24:S1-106. - PubMed
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- Thelin E.P., Zeiler F.A., Ercole A., Mondello S., Büki A., Bellander B.M., Helmy A., Menon D.K., Nelson D.W. Serial Sampling of Serum Protein Biomarkers for Monitoring Human Traumatic Brain Injury Dynamics: A Systematic Review. Front. Neurol. 2017;8:300. doi: 10.3389/fneur.2017.00300. - DOI - PMC - PubMed
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