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Case Reports
. 2018 Feb;74(2):181-182.
doi: 10.1007/s00228-017-2355-7. Epub 2017 Oct 27.

Pericarditis associated with cytarabine therapy for acute myelocytic leukemia: a case report

Xia Yang  1 , Wei Liu  1   2 , Allie Lyons  1   3 , Zaiwei Song  1 , Suodi Zhai  1   2 , Kai Hu  4
Affiliations
Case Reports

Pericarditis associated with cytarabine therapy for acute myelocytic leukemia: a case report

Xia Yang et al. Eur J Clin Pharmacol. 2018 Feb.

Abstract

Background: The incidence of cytarabine-induced pericarditis is rare. So far, only a few cases have been reported worldwide.

Description of the case: We are reporting a case of a 25-year-old male with acute myeloid leukemia (AML M2a) on chemotherapy who developed acute pericarditis after the administration of a cytarabine-containing regimen. The symptoms gradually improved after symptomatic treatment with steroids and other drugs.

Conclusions: This case demonstrates that, although pericarditis induced by cytarabine is rare, early recognition of this potentially life-threatening complication and appropriate management will usually result in the patient's recovery.

Keywords: Acute myeloid leukemia; Cytarabine; Pericarditis.

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