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Comment
. 2017 Sep;6(Suppl 4):S402-S404.
doi: 10.21037/tau.2017.03.40.

Implications of ejaculatory sperm DNA fragmentation on male infertility management

Majid Mirzazadeh  1 , Hooman Sadri-Ardekani  1   2
Affiliations
Comment

Implications of ejaculatory sperm DNA fragmentation on male infertility management

Majid Mirzazadeh et al. Transl Androl Urol. 2017 Sep.
No abstract available

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Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Clinical varicocele and ejaculatory SDF. *, varicocele repair does not have indication, if the female partner suffers from advanced age subfertility (<35) or untreatable female factor (2,3). S/A, semen analysis; SDF, sperm DNA fragmentation.
Figure 2
Figure 2
Role of SDF on recurrent miscarriage and ART failure. (A) Recurrent spontaneous miscarriage and SDF; (B) recurrent ART failure and sperm DNA fragmentation (7). *, IUI is recommended, only if the total number of rapid forward progressive sperms per ejaculate is >2 millions (7). SDF, sperms DNA fragmentation; IUI, intrauterine insemination; IVF, in vitro fertilization; ICSI, intracytoplasmic sperm injection; IMSI, intracytoplasmic morphologically selected sperm injection; ART, assisted reproductive technology.
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References

    1. World Health Organization. WHO laboratory manual for the examination and processing of human semen. Fifth edition. Geneva, WHO, 2010.
    1. Jarow J, Sigman M, Kolettis PN, et al. The Optimal Evaluation of the Infertile Male: AUA Best Practice Statement. Washington: American Urological Association Education and Research, Inc, 2011. Available online: https://www.auanet.org/education/guidelines/male-infertility-d.cfm
    1. Björndahl L, Giwercman A, Tournaye H, et al. editors. Clinical Andrology: EAU/ESAU Course Guidelines. 1 edition. CRC Press, 2010.
    1. Bungum M. Sperm DNA integrity assessment: a new tool in diagnosis and treatment of fertility. Obstet Gynecol Int 2012;2012:531042. 10.1155/2012/531042 - DOI - PMC - PubMed
    1. Agarwal A, Majzoub A, Esteves SC, et al. Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios. Transl Androl Urol 2016;5:935-50. 10.21037/tau.2016.10.03 - DOI - PMC - PubMed

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