Is sperm DNA fragmentation testing ready for prime time?

Keith A Jarvi^{1

2

3

4}

Affiliations

¹ Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
² Murray Koffler Urologic Wellness Centre, Mount Sinai Hospital, Toronto, ON, Canada.
³ Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada.
⁴ Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.

Comment

Keith A Jarvi. Transl Androl Urol. 2017 Sep.

. 2017 Sep;6(Suppl 4):S419-S421.

doi: 10.21037/tau.2017.04.05.

Keith A Jarvi^{1

2

3

4}

¹ Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
² Murray Koffler Urologic Wellness Centre, Mount Sinai Hospital, Toronto, ON, Canada.
³ Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada.
⁴ Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.

No abstract available

Conflict of interest statement

Conflicts of Interest: The author has no conflicts of interest to declare.

Sperm DNA fragmentation: overcoming standardization obstacles.
Majzoub A, Agarwal A, Esteves SC. Majzoub A, et al. Transl Androl Urol. 2017 Sep;6(Suppl 4):S422-S424. doi: 10.21037/tau.2017.07.10. Transl Androl Urol. 2017. PMID: 29082960 Free PMC article. No abstract available.

Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios.
Agarwal A, Majzoub A, Esteves SC, Ko E, Ramasamy R, Zini A. Agarwal A, et al. Transl Androl Urol. 2016 Dec;5(6):935-950. doi: 10.21037/tau.2016.10.03. Transl Androl Urol. 2016. PMID: 28078226 Free PMC article. Review.

1. Agarwal A, Majzoub A, Esteves SC, et al. Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios. Transl Androl Urol 2016;5:935-50. 10.21037/tau.2016.10.03 - DOI - PMC - PubMed
1. Practice Committee of the American Society for Reproductive Medicine The clinical utility of sperm DNA integrity testing: a guideline. Fertil Steril 2013;99:673-7. 10.1016/j.fertnstert.2012.12.049 - DOI - PubMed
1. Cooper TG, Noonan E, von Eckardstein S, et al. World Health Organization reference values for human semen characteristics. Hum Reprod Update 2010;16:231-45. 10.1093/humupd/dmp048 - DOI - PubMed
1. Boitrelle F, Guthauser B, Alter L, et al. The nature of human sperm head vacuoles: a systematic literature review. Basic Clin Androl 2013;23:3. 10.1186/2051-4190-23-3 - DOI - PMC - PubMed
1. Cissen M, Wely MV, Scholten I, et al. Measuring Sperm DNA Fragmentation and Clinical Outcomes of Medically Assisted Reproduction: A Systematic Review and Meta-Analysis. PLoS One 2016;11:e0165125. 10.1371/journal.pone.0165125 - DOI - PMC - PubMed