Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2017 Sep;6(Suppl 4):S553-S556.
doi: 10.21037/tau.2017.03.11.

Evaluation of sperm DNA structure, fragmentation and decondensation: an essential tool in the assessment of male infertility

Yves Menezo  1 , Patrice Clement  2 , Edouard Amar  3
Affiliations
Comment

Evaluation of sperm DNA structure, fragmentation and decondensation: an essential tool in the assessment of male infertility

Yves Menezo et al. Transl Androl Urol. 2017 Sep.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
The one carbon cycle: its impact on the process of methylation and synthesis of three major antioxidant molecules. CBS, cystathionine beta synthase; MS, methionine synthase; SAH, S Adenosyl Homocysteine; SAM, S Adenosyl Methionine; CoQ10 synthesis need 3 SAdenosyl methionine for its synthesis.
See this image and copyright information in PMC

Comment in

  • The complex nature of the sperm DNA damage process.
    Esteves SC, Agarwal A, Majzoub A. Esteves SC, et al. Transl Androl Urol. 2017 Sep;6(Suppl 4):S557-S559. doi: 10.21037/tau.2017.05.13. Transl Androl Urol. 2017. PMID: 29082946 Free PMC article. No abstract available.

Comment on

References

    1. Ménézo Y, Dale B, Cohen M. DNA damage and repair in human oocytes and embryos: a review. Zygote 2010;18:357-65. 10.1017/S0967199410000286 - DOI - PubMed
    1. Belloc S, Benkhalifa M, Junca AM, et al. Paternal age and sperm DNA decay: discrepancy between chromomycin and aniline blue staining. Reprod Biomed Online 2009;19:264-9. 10.1016/S1472-6483(10)60083-1 - DOI - PubMed
    1. Belloc S, Cohen-Bacrie P, Benkhalifa M, et al. Effect of maternal and paternal age on pregnancy and miscarriage rates after intrauterine insemination. Reprod Biomed Online 2008;17:392-7. 10.1016/S1472-6483(10)60223-4 - DOI - PubMed
    1. Guérin P, Matillon C, Bleau G, et al. Impact of sperm DNA fragmentation on ART outcome. Gynecol Obstet Fertil 2005;33:665-8. - PubMed
    1. Junca A, Gonzalez Marti B, Tosti E, et al. Sperm nucleus decondensation, hyaluronic acid (HA) binding and oocyte activation capacity: different markers of sperm immaturity? Case reports. J Assist Reprod Genet 2012;29:353-5. 10.1007/s10815-012-9710-5 - DOI - PMC - PubMed

LinkOut - more resources