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Book

Prolactinoma

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Prolactinoma

Rajini Kanth R. Yatavelli et al.
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Excerpt

Prolactin-secreting tumors of the pituitary gland are called prolactinomas. It is the most common secretory tumor of the pituitary gland accounting for up to 40% of total pituitary adenomas. Prolactinomas cause a wide variety of symptoms, either due to mass effect of the tumor or due to hypersecretion of prolactin. Based on the size of the tumors, prolactinomas can be classified as micro prolactinoma (smaller than 10 mm), macroprolactinoma (larger than 10 mm), or giant prolactinoma (larger than 4 cm). Hyperprolactinemia is not always due to prolactinoma, and other causes like pregnancy, drugs, hypothyroidism, and pituitary stalk effect due to other pituitary tumors should be considered in the differential.

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Conflict of interest statement

Disclosure: Rajini Kanth Yatavelli declares no relevant financial relationships with ineligible companies.

Disclosure: Kamal Bhusal declares no relevant financial relationships with ineligible companies.

References

    1. Pekic S, Soldatovic I, Miljic D, Stojanovic M, Doknic M, Petakov M, Popovic V. Familial Cancer Clustering in Patients with Prolactinoma. Horm Cancer. 2019 Feb;10(1):45-50. - PMC - PubMed
    1. Cooper O, Greenman Y. Dopamine Agonists for Pituitary Adenomas. Front Endocrinol (Lausanne) 2018;9:469. - PMC - PubMed
    1. Araújo C, Marques O, Almeida R, Santos MJ. Macroprolactinomas: longitudinal assessment of biochemical and imaging therapeutic responses. Endocrine. 2018 Nov;62(2):470-476. - PubMed
    1. Atluri S, Sarathi V, Goel A, Boppana R, Shivaprasad C. Etiological Profile of Galactorrhoea. Indian J Endocrinol Metab. 2018 Jul-Aug;22(4):489-493. - PMC - PubMed
    1. Saleem M, Martin H, Coates P. Prolactin Biology and Laboratory Measurement: An Update on Physiology and Current Analytical Issues. Clin Biochem Rev. 2018 Feb;39(1):3-16. - PMC - PubMed

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