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Book

Physiology, Pancreas

Suzan A. Kamel-ElSayed  1 , Sandeep Mukherjee  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Physiology, Pancreas

Suzan A. Kamel-ElSayed et al.
Free Books & Documents

Excerpt

The pancreas is a composite organ, which has exocrine and endocrine functions. The endocrine portion is arranged as discrete islets of Langerhans, which are composed of five different endocrine cell types (alpha, beta, delta, epsilon, and upsilon) secreting at least five hormones including glucagon, insulin, somatostatin, ghrelin, and pancreatic polypeptide, respectively.

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Conflict of interest statement

Disclosure: Suzan Kamel-ElSayed declares no relevant financial relationships with ineligible companies.

Disclosure: Sandeep Mukherjee declares no relevant financial relationships with ineligible companies.

References

    1. O'Toole TJ, Sharma S. StatPearls [Internet] StatPearls Publishing; Treasure Island (FL): 2023. Jul 24, Physiology, Somatostatin. - PubMed
    1. Capurso G, Traini M, Piciucchi M, Signoretti M, Arcidiacono PG. Exocrine pancreatic insufficiency: prevalence, diagnosis, and management. Clin Exp Gastroenterol. 2019;12:129-139. - PMC - PubMed
    1. Matschinsky FM, Wilson DF. The Central Role of Glucokinase in Glucose Homeostasis: A Perspective 50 Years After Demonstrating the Presence of the Enzyme in Islets of Langerhans. Front Physiol. 2019;10:148. - PMC - PubMed
    1. Allen N, Gupta A. Current Diabetes Technology: Striving for the Artificial Pancreas. Diagnostics (Basel) 2019 Mar 15;9(1) - PMC - PubMed
    1. Vettoretti M, Facchinetti A. Combining continuous glucose monitoring and insulin pumps to automatically tune the basal insulin infusion in diabetes therapy: a review. Biomed Eng Online. 2019 Mar 29;18(1):37. - PMC - PubMed

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