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Book

Prediabetes

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Prediabetes

Shantal Alvarez et al.
Free Books & Documents

Excerpt

Prediabetes is a precursor before the diagnosis of diabetes mellitus. Adults with prediabetes often may show no signs or symptoms of diabetes but will have blood sugar levels higher than normal. The normal blood glucose level is between 70 mg/dL to 99 mg/dL. In patients with prediabetes, you can expect to see blood glucose levels elevated between 110 mg/dL to - 125 mg/dL. However, these levels do not meet the required criteria for a diagnosis of diabetes mellitus. For this reason, many people are not aware that they are living with prediabetes.

In addition to type 2 diabetes, prediabetes is a risk factor for the development of cardiovascular disease, and stroke. Once diagnosed with prediabetes patients should be checked for progression to type 2 diabetes every one to two years. If screening is negative for prediabetes, repeat screening should be carried out every 3 years as per the United States Preventive Services Task Force (USPSTF). Lifestyle changes through improved nutrition and physical activity are the firstline treatment for preventing the transition from prediabetes to diabetes which can be as high as 70%.

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Conflict of interest statement

Disclosure: Shantal Alvarez declares no relevant financial relationships with ineligible companies.

Disclosure: Ryan Coffey declares no relevant financial relationships with ineligible companies.

Disclosure: Priyanka Mathias declares no relevant financial relationships with ineligible companies.

Disclosure: Amit Algotar declares no relevant financial relationships with ineligible companies.

References

    1. Horstman C, Aronne L, Wing R, Ryan DH, Johnson WD. Implementing an Online Weight-Management Intervention to an Employee Population: Initial Experience with Real Appeal. Obesity (Silver Spring) 2018 Nov;26(11):1704-1708. - PMC - PubMed
    1. Moin T, Damschroder LJ, AuYoung M, Maciejewski ML, Havens K, Ertl K, Vasti E, Weinreb JE, Steinle NI, Billington CJ, Hughes M, Makki F, Youles B, Holleman RG, Kim HM, Kinsinger LS, Richardson CR. Results From a Trial of an Online Diabetes Prevention Program Intervention. Am J Prev Med. 2018 Nov;55(5):583-591. - PMC - PubMed
    1. Stepanek L, Horakova D, Nakladalova M, Cibickova L, Karasek D, Zadrazil J. Significance of prediabetes as a nosological entity. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2018 Sep 24; - PubMed
    1. DiBonaventura M, Nicolucci A, Meincke H, Le Lay A, Fournier J. Obesity in Germany and Italy: prevalence, comorbidities, and associations with patient outcomes. Clinicoecon Outcomes Res. 2018;10:457-475. - PMC - PubMed
    1. Granados A, Gebremariam A, Gidding SS, Terry JG, Carr JJ, Steffen LM, Jacobs DR, Lee JM. Association of abdominal muscle composition with prediabetes and diabetes: The CARDIA study. Diabetes Obes Metab. 2019 Feb;21(2):267-275. - PMC - PubMed

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