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Book

Physiology, Cardiac Cycle

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Physiology, Cardiac Cycle

Joshua D. Pollock et al.
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Excerpt

The cardiac cycle is a series of pressure changes within the heart. These pressure changes result in blood movement through different chambers of the heart and the body as a whole. These pressure changes originate as conductive electrochemical changes within the myocardium that result in the concentric contraction of cardiac muscle. Valves within the heart direct blood movement, which leads to the organized propulsion of blood to the next chamber. This rhythmic sequence causes changes in pressure and volume that are often seen graphically in the form of a Wiggers diagram or venous pressure tracings (see Image. Wiggers Diagram). This information is vital to the clinical understanding of cardiac auscultation, pathology, and interventions.

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Conflict of interest statement

Disclosure: Joshua Pollock declares no relevant financial relationships with ineligible companies.

Disclosure: Amgad Makaryus declares no relevant financial relationships with ineligible companies.

References

    1. Nishimura RA, Borlaug BA. Diastology for the clinician. J Cardiol. 2019 Jun;73(6):445-452. - PubMed
    1. DeMers D, Wachs D. StatPearls [Internet] StatPearls Publishing; Treasure Island (FL): 2023. Apr 10, Physiology, Mean Arterial Pressure. - PubMed
    1. Chung CS. How myofilament strain and strain rate lead the dance of the cardiac cycle. Arch Biochem Biophys. 2019 Mar 30;664:62-67. - PMC - PubMed
    1. Castillo Moya A, Del Pozo Bascuñán P. [Cardiopulmonary Interactions: From Physiology to Clinic]. Rev Chil Pediatr. 2018 Oct;89(5):582-591. - PubMed
    1. Koschate J, Drescher U, Werner A, Thieschäfer L, Hoffmann U. Cardiovascular regulation: associations between exercise and head-up tilt. Can J Physiol Pharmacol. 2019 Aug;97(8):738-745. - PubMed

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