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Book

Granuloma Annulare

Shawn J. Schmieder, Chelsea D. Harper  1 , George J. Schmieder  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Granuloma Annulare

Shawn J. Schmieder et al.
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Excerpt

Granuloma annulare (GA) is a cutaneous granulomatous disease of unknown etiology. It is the most common non-infectious granulomatous disease. The disease is benign and often self-limited. Granuloma annulare usually presents as erythematous plaques or papules arranged in an annular configuration on the upper extremities. In addition to the more common presentation, termed localized granuloma annulare, other clinical variants of granuloma annulare include generalized, perforating, patch, and subcutaneous. Despite being a benign disease, it can be associated with more serious conditions such as HIV or malignancy.

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Conflict of interest statement

Disclosure: Shawn Schmieder declares no relevant financial relationships with ineligible companies.

Disclosure: Chelsea Harper declares no relevant financial relationships with ineligible companies.

Disclosure: George Schmieder declares no relevant financial relationships with ineligible companies.

References

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    1. Ronen S, Rothschild M, Suster S. The interstitial variant of granuloma annulare: Clinicopathologic study of 69 cases with a comparison with conventional granuloma annulare. J Cutan Pathol. 2019 Jul;46(7):471-478. - PubMed
    1. Gabaldón VH, Haro-González-Vico V. Lack of an association between generalized granuloma annulare and malignancy: A case-control study. J Am Acad Dermatol. 2019 Jun;80(6):1799-1800. - PubMed
    1. Imadojemu S, Rosenbach M. Advances in Inflammatory Granulomatous Skin Diseases. Dermatol Clin. 2019 Jan;37(1):49-64. - PubMed
    1. Errichetti E, Stinco G. Dermatoscopy of Granulomatous Disorders. Dermatol Clin. 2018 Oct;36(4):369-375. - PubMed

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