Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Acute Cholecystitis

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Acute Cholecystitis

Mark W. Jones et al.
Free Books & Documents

Excerpt

Acute cholecystitis involves inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct by a gallstone. In fewer cases, impaired gallbladder emptying due to cholestasis and acute illness contributes to the condition. Surgical intervention remains the preferred treatment, though selected patients may benefit from conservative management with antibiotics and supportive care based on clinical context.

Cholecystitis can occur with or without gallstones and is classified as either acute or chronic. Both men and women experience this condition, although women tend to have a higher susceptibility. The acute form typically presents with well-recognized signs and symptoms; however, clinical overlap with disorders, eg, peptic ulcer disease, irritable bowel syndrome, cardiac conditions, and pancreatitis, can complicate diagnosis.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Mark Jones declares no relevant financial relationships with ineligible companies.

Disclosure: Gregory Santos declares no relevant financial relationships with ineligible companies.

Disclosure: Parth Patel declares no relevant financial relationships with ineligible companies.

Disclosure: Maria O'Rourke declares no relevant financial relationships with ineligible companies.

References

    1. Fu Y, Pang L, Dai W, Wu S, Kong J. Advances in the Study of Acute Acalculous Cholecystitis: A Comprehensive Review. Dig Dis. 2022;40(4):468-478. - PubMed
    1. Burmeister G, Hinz S, Schafmayer C. [Acute Cholecystitis]. Zentralbl Chir. 2018 Aug;143(4):392-399. - PubMed
    1. Walsh K, Goutos I, Dheansa B. Acute Acalculous Cholecystitis in Burns: A Review. J Burn Care Res. 2018 Aug 17;39(5):724-728. - PubMed
    1. Kohga A, Suzuki K, Okumura T, Yamashita K, Isogaki J, Kawabe A, Kimura T. Is postponed laparoscopic cholecystectomy justified for acute cholecystitis appearing early after onset? Asian J Endosc Surg. 2019 Jan;12(1):69-73. - PubMed
    1. Ahmed M. Functional, Diagnostic and Therapeutic Aspects of Bile. Clin Exp Gastroenterol. 2022;15:105-120. - PMC - PubMed

Publication types

LinkOut - more resources