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Book

Autoimmune Hepatitis

Catherine D. Linzay  1 , Bashar Sharma  2 , Sudha Pandit  1
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Autoimmune Hepatitis

Catherine D. Linzay et al.
Free Books & Documents

Excerpt

Autoimmune hepatitis refers to chronic and progressive inflammation of the liver from an unknown cause. The proposed mechanism for the development of autoimmune hepatitis is thought to be the interplay of genetic predisposition, an environmental trigger, and failure of the native immune system resulting in chronic inflammation of hepatocytes and subsequent fibrosis of the liver. There are two known types of autoimmune hepatitis. Type 1 is distinguished by the presence of anti-smooth muscle antibodies (ASMA) with or without anti-nuclear antibodies (ANA). Type 2 autoimmune hepatitis presents with positive anti-liver/anti-kidney microsome (anti-LMK) type 1 antibodies or anti-liver cytosol (anti-LC) type 1 antibodies.

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Conflict of interest statement

Disclosure: Catherine Linzay declares no relevant financial relationships with ineligible companies.

Disclosure: Bashar Sharma declares no relevant financial relationships with ineligible companies.

Disclosure: Sudha Pandit declares no relevant financial relationships with ineligible companies.

References

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