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Randomized Controlled Trial
. 2017 Sep;17(3):603-613.
doi: 10.4314/ahs.v17i3.2.

Efficacy of combined traditional Chinese medicine spray with premature ejaculation desensitization therapy for the treatment of primary premature ejaculation

Ying-Dong Cui  1 , Shu-Bin Hu  1 , Bo Wu  1 , Shi-Jun Li  1 , Kui Xiang  1 , Zhao-Lin Liao  1 , Hui-Ping Zhang  2 , Chang-Hong Zhu  2 , Meng Rao  2
Affiliations
Randomized Controlled Trial

Efficacy of combined traditional Chinese medicine spray with premature ejaculation desensitization therapy for the treatment of primary premature ejaculation

Ying-Dong Cui et al. Afr Health Sci. 2017 Sep.

Abstract

Objectives: We recommend a new kind of spray made from eight kinds of traditional Chinese medicine, we aimed to investigate the safety and clinical efficacy of combined traditional Chinese medicine spray (TCMS) with premature ejaculation desensitization therapy (PEDT) for the treatment of primary premature ejaculation (PPE).

Methods: A total of 90 patients with PPE were randomly assigned to receive TCMS, PEDT monotherapy or TCMS plus PEDT combination therapy for 6 weeks. Intravaginal ejaculation latency time (IELT) and Chinese index of sexual function for premature ejaculation (CIPE-5) were measured to evaluate the effect of each treatment.

Results: Eighty six (86) participants completed the study voluntarily. Both IELT and CIPE-5 in these three groups increased after treatment when compared with baseline levels (p< 0.01). IELT and CIPE-5 after treatment in TCMS plus PEDT group were significantly higher than those in the other two groups (both p <0.05). Additionally, clinical efficacy in TCMS plus PEDT group (89.7%) was significantly higher than in TCMS (65.5%) and PEDT group (67.9%) (p< 0.01).

Conclusion: The self-made TCMS was safe and effective for the treatment of PPE, a combination of TCMS and PEDT therapy was more effective than the TCMS or PEDT monotherapy.

Keywords: Chinese index of sexual function for premature ejaculation (CIPE-5); Intravaginal ejaculation latency time (IELT); Primary premature ejaculation (PPE); premature ejaculation desensitization training therapy (PEDT); traditional Chinese mdicine spray (TCMS).

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Figures

Figure 1
Figure 1
Flow chart of the study.
Figure 2
Figure 2
Clinical efficacy rate in each group. * Compared with TCMS group (p< 0.05); #compared with PEDTgroup (p< 0.05); No significant difference exists between TCMS and PEDT group
See this image and copyright information in PMC

References

    1. Laumann EO, Nicolosi A, Glasser DB, Paik A, Gingell C, Moreira E, Wang T, Group GI. Sexual problems among women and men aged 40–80 y: prevalence and correlates identified in the Global Study of Sexual Attitudes and Behaviors. Int J Impot Res. 2005;17(1):39–57. - PubMed
    1. Porst H, Montorsi F, Rosen RC, Gaynor L, Grupe S, Alexander J. The Premature Ejaculation Prevalence and Attitudes (PEPA) survey: prevalence, comorbidities, and professional help-seeking. Eur Urol. 2007;51(3):816–823. discussion 824. - PubMed
    1. Rosen RC, Althof S. Impact of premature ejaculation: the psychological, quality of life, and sexual relationship consequences. J Sex Med. 2008;5(6):1296–1307. - PubMed
    1. Rowland DL, Motofei IG. The aetiology of premature ejaculation and the mind-body problem: implications for practice. Int J Clin Pract. 2007;61(1):77–82. - PubMed
    1. Xin ZC, Choi YD, Seong DH, Choi HK. Sensory evoked potential and effect of SS-cream in premature ejaculation. Yonsei Med J. 1995;36(5):397–401. - PubMed

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