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Case Reports
. 2017:2017:4973573.
doi: 10.1155/2017/4973573. Epub 2017 Sep 20.

Epithelial-Myoepithelial Carcinoma of the Base of Tongue with Possible Lung Metastases

Michael Y Chen  1 , Vipul Vyas  1 , Ryan Sommerville  1
Affiliations
Case Reports

Epithelial-Myoepithelial Carcinoma of the Base of Tongue with Possible Lung Metastases

Michael Y Chen et al. Case Rep Otolaryngol. 2017.

Abstract

Background: Epithelial-myoepithelial carcinomas are rare neoplasms usually arising from the salivary glands. There is limited evidence in the literature on their prognosis in the base of the tongue but other cases have resolved without recurrence.

Methods: The patient underwent biopsies demonstrating the diagnosis of epithelial-myoepithelial carcinoma of the base of tongue and a PET scan showed multiple bilateral rounded pulmonary nodules.

Results: The patient declined chemotherapy and radiotherapy to maximise his quality of life and passed away under management from palliative care several months later.

Discussion: This is the only case in the literature of this type of carcinoma in the base of the tongue resulting in metastases and a poor prognosis. The case highlights the importance of checking for metastases in such lesions and their potentially serious outcomes if left untreated.

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Figures

Figure 1
Figure 1
MRI of lesion in base of tongue.
Figure 2
Figure 2
Haematoxylin and eosin (H&E) stain at ×40 magnification.
Figure 3
Figure 3
H&E stain demonstrating perineural invasion of the tumour.
See this image and copyright information in PMC

References

    1. Vázquez A., Patel T. D., Daguillo C. M., et al. Epithelial-Myoepithelial Carcinoma of the Salivary Glands. Otolaryngology - Head and Neck Surgery (United States) 2015;153(4):569–574. doi: 10.1177/0194599815594788. - DOI - PubMed
    1. Peters P., Repanos C., Earnshaw J., et al. Epithelial-myoepithelial carcinoma of the tongue base: A case for the case-report and review of the literature. Head and Neck Oncology. 2010;2(1, article no. 4) doi: 10.1186/1758-3284-2-4. - DOI - PMC - PubMed
    1. Seethala R. R., Leon Barnes E., Hunt J. L. Epithelial-myoepithelial carcinoma: A review of the clinicopathologic spectrum and immunophenotypic characteristics in 61 tumors of the salivary glands and upper aerodigestive tract. American Journal of Surgical Pathology. 2007;31(1):44–57. doi: 10.1097/01.pas.0000213314.74423.d8. - DOI - PubMed
    1. Puri T., Singh K., Sharma D. N., Khurana N. Epithelial-myoepithelial carcinoma of the base of tongue: pathology and management. Indian J Cancer. 2004;41(3):138–140. - PubMed
    1. Kumai Y., Ogata N., Yumoto E. Epithelial-myoepithelial carcinoma in the base of the tongue: a case report. American Journal of Otolaryngology—Head and Neck Medicine and Surgery. 2006;27(1):58–60. doi: 10.1016/j.amjoto.2005.05.016. - DOI - PubMed

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