Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2017 Nov 14;114(46):E9759-E9760.
doi: 10.1073/pnas.1716444114. Epub 2017 Oct 30.

Theory, simulations, and experiments show that proteins fold by multiple pathways

William A Eaton  1 , Peter G Wolynes  2   3
Affiliations
Comment

Theory, simulations, and experiments show that proteins fold by multiple pathways

William A Eaton et al. Proc Natl Acad Sci U S A. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Comment in

  • Reply to Eaton and Wolynes: How do proteins fold?
    Englander SW, Mayne L. Englander SW, et al. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9761-E9762. doi: 10.1073/pnas.1716929114. Epub 2017 Oct 30. Proc Natl Acad Sci U S A. 2017. PMID: 29087353 Free PMC article. No abstract available.

Comment on

  • The case for defined protein folding pathways.
    Englander SW, Mayne L. Englander SW, et al. Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8253-8258. doi: 10.1073/pnas.1706196114. Epub 2017 Jun 19. Proc Natl Acad Sci U S A. 2017. PMID: 28630329 Free PMC article.

References

    1. Englander SW, Mayne L. The case for defined protein folding pathways. Proc Natl Acad Sci USA. 2017;114:8253–8258. - PMC - PubMed
    1. Bai Y, Sosnick TR, Mayne L, Englander SW. Protein folding intermediates: Native-state hydrogen exchange. Science. 1995;269:192–197. - PMC - PubMed
    1. Wolynes PG, Eaton WA, Fersht AR. Chemical physics of protein folding. Proc Natl Acad Sci USA. 2012;109:17770–17771. - PMC - PubMed
    1. Craig PO, et al. Prediction of native-state hydrogen exchange from perfectly funneled energy landscapes. J Am Chem Soc. 2011;133:17463–17472. - PMC - PubMed
    1. Baldwin RL. Clash between energy landscape theory and foldon-dependent protein folding. Proc Natl Acad Sci USA. 2017;114:8442–8443. - PMC - PubMed

LinkOut - more resources